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Phase

Phase 1/2 1

Status

Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 36Tumor-Agnostic 22Thoracic 5Endocrine 4Gynecologic 3Sarcoma 2Lymphoid 2Head & Neck 2Genitourinary 2CNS 2Breast 2Other solid neoplasm 1NET 1Dermatologic 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 13Advanced Solid Tumors 6Solid Tumors 5Advanced Solid Tumor 5Solid Tumor 4Mesothelioma 2Triple Negative Breast Neoplasms 1Thymoma 1Stomach Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Sarcoma 1Retinoblastoma 1Resectable Colon Cancer 1Pseudomyxoma Peritonei 1Peritoneal Neoplasms 1Neuroblastoma 1Neoplasms 1Neoplasm Metastasis 1Mesothelioma, Malignant 1Melanoma 1Malignant Solid Tumour 1MSI-H Advanced Colorectal Cancer 1Esophageal Neoplasms 1Endometrial Neoplasms 1Choroid Plexus Neoplasms 1Childhood Central Nervous System Choriocarcinoma 1Central Nervous System Neoplasms 1Carcinoma, Transitional Cell 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1

Interventions

pembrolizumab 4Cisplatin 3Carboplatin 3budigalimab 2Pemetrexed 2Paclitaxel 2Immunotherapy 2Etoposide 2Drug Therapy 2Docetaxel 2Cyclophosphamide 2venetoclax 1trametinib 1spartalizumab 1sargramostim 1rovalpituzumab tesirine 1ribociclib 1poly ICLC 1fludarabine 1enzalutamide 1entinostat 1belinostat 1UV1 vaccine 1Tomography, Optical Coherence 1Thrombopoietin 1Sunitinib 1Sirolimus 1Quality of Life 1Polymerase Chain Reaction 1Patient Reported Outcome Measures 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms × Leucovorin × Other solid neoplasm × Clear all
NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

NuCana plc

Phase 1/2 Terminated
19 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

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