Announcements Trials
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Phase

Phase 1 2

Status

Active not recruiting 2

Sponsor Class

INDUSTRY 6OTHER 2NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 58CNS 8Gynecologic 7Gastrointestinal 7Dermatologic 7Thoracic 4Genitourinary 4Plasma cell 2Other solid neoplasm 2Breast 2NET 1Lymphoid 1Head & Neck 1Endocrine 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 184Mesothelioma, Malignant 183Mesothelioma 145Solid Tumor 135Retinoblastoma 96Solid Tumors 86Advanced Solid Tumor 60Advanced Solid Tumors 50Solid Tumor, Adult 47Hematopoietic and Lymphatic System Neoplasm 47Carcinoma, Non-Small-Cell Lung 42Lung Neoplasms 33Sarcoma 28Hematopoietic and Lymphoid System Neoplasm 23Small Cell Lung Carcinoma 21Pancreatic Neoplasms 20Stomach Neoplasms 19Neuroblastoma 19Melanoma 19Carcinoma, Renal Cell 19Ovarian Neoplasms 18Neoplasms 17Wilms Tumor 15Colorectal Neoplasms 15Breast Neoplasms 15Osteosarcoma 13Solitary Fibrous Tumor, Pleural 12Rhabdomyosarcoma 12Refractory Solid Tumors 12Esophageal Neoplasms 12

Interventions

pembrolizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Sarcoma, Synovial × Other solid neoplasm × Clear all
NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT03618381 2025-11-20

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
44 enrolled
CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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