Announcements Trials
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Phase

Phase 2 2Phase 1 1

Status

Active not recruiting 2Withdrawn 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Thoracic 5Sarcoma 5Gastrointestinal 5Other solid neoplasm 3Head & Neck 3Gynecologic 2Genitourinary 2Dermatologic 2NET 1Endocrine 1Breast 1

Conditions

Advanced Solid Tumor 12Solid Tumor 6Advanced Solid Tumors 5Sarcoma 3Uterine Cervical Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Solid Tumors 2Small Cell Lung Carcinoma 2Mesothelioma 2Melanoma 2Carcinoma, Renal Cell 2Anus Neoplasms 2Advanced Solid Tumour 2Uveal Melanoma 1Triple Negative Breast Neoplasms 1Thyroid Neoplasms 1Testicular Germ Cell Tumor 1Stomach Neoplasms 1Solid Tumor, Adult 1Neoplasms, Unknown Primary 1Metastatic Solid Tumors 1Mesothelioma, Malignant 1Malignant Solid Tumors 1MSI-H/dMMR Solid Tumors 1MSI-H Colorectal Cancer 1Locally Advanced or Metastatic Solid Tumors for Phase 1, Dose Escalation and Phase 2 Safety Lead-in 1Locally Advanced or Metastatic Solid Tumors 1Locally Advanced and Metastatic Solid Tumors 1Colorectal Neoplasms 1Cholangiocarcinoma 1

Interventions

Cyclophosphamide 6Thiotepa 5Granulocyte Colony-Stimulating Factor 4Filgrastim 4Etoposide 4Cisplatin 4Busulfan 4tislelizumab 3Melphalan 3Carboplatin 3tazemetostat 2regorafenib 2pembrolizumab 2belinostat 2Topotecan 2Temozolomide 2Radiotherapy 2Peripheral Blood Stem Cell Transplantation 2Mesna 2Ifosfamide 2Doxorubicin 2spartalizumab 1sodium thiosulfate 1sargramostim 1pegylated granulocyte colony-stimulating factor 1fludarabine phosphate 1fludarabine 1etoposide phosphate 1entinostat 1cixutumumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Sarcoma × tislelizumab × Other solid neoplasm × Clear all
NCT05238883 2025-11-21

A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

HiFiBiO Therapeutics

Phase 1 Active not recruiting
72 enrolled
DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Melanoma, Mesothelioma, Sarcoma, Stomach Neoplasms

NCT04802876 2025-03-21

ACROPOLI

SOLTI Breast Cancer Research Group

Phase 2 Active not recruiting
184 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Adenocarcinoma Of Esophagus, Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Uveal Melanoma, Anus Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasms, Unknown Primary, Sarcoma, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT05582031 2023-06-07

REFIT-MSS

Translational Research in Oncology

Phase 2 Withdrawn
GastrointestinalOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Anus Neoplasms, Sarcoma, Colorectal Neoplasms, Small Cell Lung Carcinoma

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