Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 1/2 1

Status

Completed 3

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Other solid neoplasm 3

Conditions

Advanced Solid Tumors 357Unspecified Adult Solid Tumor, Protocol Specific 302Advanced Solid Tumor 274Solid Tumor 237Solid Tumors 233Mesothelioma 84Mesothelioma, Malignant 79Solid Tumor, Adult 65Carcinoma, Non-Small-Cell Lung 57Ovarian Neoplasms 38Melanoma 35Lung Neoplasms 29Advanced or Metastatic Solid Tumors 27Neoplasms 26Carcinoma, Renal Cell 26Uterine Cervical Neoplasms 25Stomach Neoplasms 25Pancreatic Neoplasms 25Solid Tumours 24Sarcoma 24Colorectal Neoplasms 24Retinoblastoma 22Esophageal Neoplasms 22Advanced Malignant Solid Tumors 22Unspecified Childhood Solid Tumor, Protocol Specific 21Squamous Cell Carcinoma of Head and Neck 20Breast Neoplasms 20Advanced Solid Tumours 20Triple Negative Breast Neoplasms 19Small Cell Lung Carcinoma 19

Interventions

selitrectinib 2larotrectinib 1Suspensions 1Solutions 1Receptor Protein-Tyrosine Kinases 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Solid Tumors Harboring NTRK Fusion × Other solid neoplasm × Clear all
NCT02122913 2026-02-05

A Study to Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer

Bayer

Phase 1 Completed
75 enrolled 2 FDA
Other solid neoplasm

Solid Tumors Harboring NTRK Fusion

NCT04771390 2021-08-25

Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants

Bayer

Phase 1 Completed
52 enrolled
Other solid neoplasm

Solid Tumors Harboring NTRK Fusion

NCT04275960 2020-12-29

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Bayer

Phase 1 Completed
24 enrolled
Other solid neoplasm

Solid Tumors Harboring NTRK Fusion

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