Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 2

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 7Gastrointestinal 4Genitourinary 3Other solid neoplasm 2Sarcoma 1Head & Neck 1Gynecologic 1Dermatologic 1Breast 1

Conditions

Mesothelioma 58Advanced Solid Tumors 52Mesothelioma, Malignant 51Solid Tumors 43Solid Tumor 35Advanced Solid Tumor 23Carcinoma, Non-Small-Cell Lung 20Lung Neoplasms 12Ovarian Neoplasms 10Melanoma 10Esophageal Neoplasms 10Stomach Neoplasms 9Small Cell Lung Carcinoma 9Retinoblastoma 9Carcinoma, Renal Cell 9Unspecified Adult Solid Tumor, Protocol Specific 8Solitary Fibrous Tumor, Pleural 8Sarcoma 8Pancreatic Neoplasms 8Neoplasm Metastasis 8Breast Neoplasms 7Uterine Cervical Neoplasms 6Malignant Solid Tumor 6Triple Negative Breast Neoplasms 5Squamous Cell Carcinoma of Head and Neck 5Solid Tumor, Adult 5Osteosarcoma 5Metastatic Solid Tumors 5Liver Neoplasms 5Colorectal Neoplasms 5

Interventions

pembrolizumab 1Plicamycin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Has results × Thymus Neoplasms × Other solid neoplasm × Clear all
NCT04234113 2026-03-27

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Sotio Biotech Inc.

Phase 1 Terminated
115 enrolled 43 charts
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02859415 2022-04-05

Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
3 enrolled 10 charts
GastrointestinalGenitourinaryOther solid neoplasmSarcomaThoracic

Esophageal Neoplasms, Kidney Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Germ Cell and Embryonal, Sarcoma, Thymus Neoplasms, Colorectal Neoplasms

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