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Phase

Phase 1 5Phase 1/2 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 2Sarcoma 1Other solid neoplasm 1Genitourinary 1Gastrointestinal 1

Conditions

Advanced Solid Tumor 104Advanced Solid Tumors 92Solid Tumor 69Mesothelioma 42Mesothelioma, Malignant 41Solid Tumors 37Carcinoma, Non-Small-Cell Lung 25Solid Tumor, Adult 22Stomach Neoplasms 15Ovarian Neoplasms 15Esophageal Neoplasms 15Melanoma 13Colorectal Neoplasms 13Carcinoma, Renal Cell 13Endometrial Neoplasms 11Unspecified Adult Solid Tumor, Protocol Specific 10Pancreatic Neoplasms 10Neoplasms 10Neoplasm Metastasis 10Advanced Malignant Solid Tumor 10Uterine Cervical Neoplasms 9Malignant Solid Tumor 9Lung Neoplasms 9Breast Neoplasms 9Triple Negative Breast Neoplasms 8Squamous Cell Carcinoma of Head and Neck 8Sarcoma 8Advanced or Metastatic Solid Tumors 8Carcinoma, Hepatocellular 7Small Cell Lung Carcinoma 6

Interventions

Plicamycin 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Thymus Neoplasms × Other solid neoplasm × Clear all
NCT02859415 2022-04-05

Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
3 enrolled 10 charts
GastrointestinalGenitourinaryOther solid neoplasmSarcomaThoracic

Esophageal Neoplasms, Kidney Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Germ Cell and Embryonal, Sarcoma, Thymus Neoplasms, Colorectal Neoplasms

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