Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 2Recruiting 1

Sponsor Class

OTHER 7INDUSTRY 4NIH 3

Study Type

Interventional 2Observational 1

Sponsor

Cancer Type

Thoracic 9Other solid neoplasm 3Genitourinary 2Gastrointestinal 2Sarcoma 1Gynecologic 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 141Mesothelioma, Malignant 49Mesothelioma 24Lung Neoplasms 18Unspecified Childhood Solid Tumor, Protocol Specific 15Carcinoma, Non-Small-Cell Lung 14Solitary Fibrous Tumor, Pleural 11Pancreatic Neoplasms 11Esophageal Neoplasms 11Sarcoma 10Ovarian Neoplasms 9Small Cell Lung Carcinoma 8Uterine Cervical Neoplasms 7Stomach Neoplasms 7Colonic Neoplasms 7Squamous Cell Carcinoma of Head and Neck 6Retinoblastoma 6Neoplasms 6Carcinoma, Ovarian Epithelial 6Breast Neoplasms 6Thymoma 5Salivary Gland Neoplasms 5Fallopian Tube Neoplasms 5Carcinoma, Hepatocellular 5Astrocytoma 5Urinary Bladder Neoplasms 4Osteosarcoma 4Oligodendroglioma 4Neuroblastoma 4Neoplasm Metastasis 4

Interventions

fludarabine 1Plicamycin 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
NIH × Thymus Neoplasms × Other solid neoplasm × Clear all
NCT06885697 2026-06-04

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
100 enrolled
GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

NCT01851395 2026-05-05

Rapid Autopsy and Procurement of Cancer Tissue

National Institutes of Health Clinical Center (CC)

Terminated
32 enrolled
Other solid neoplasmThoracic

Lung Neoplasms, Mesothelioma, Thymus Neoplasms, Urogenital Neoplasms

NCT02859415 2022-04-05

Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
3 enrolled 10 charts
GastrointestinalGenitourinaryOther solid neoplasmSarcomaThoracic

Esophageal Neoplasms, Kidney Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Germ Cell and Embryonal, Sarcoma, Thymus Neoplasms, Colorectal Neoplasms

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