Announcements Trials
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Phase

Phase 1 2

Status

Withdrawn 1Active not recruiting 1

Sponsor Class

INDUSTRY 24OTHER 5NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 46Gynecologic 12Thoracic 6Genitourinary 6Gastrointestinal 5Dermatologic 3Sarcoma 2Other solid neoplasm 2Head & Neck 2CNS 2Plasma cell 1Other hematologic neoplasm 1

Conditions

Unspecified Adult Solid Tumor, Protocol Specific 141Mesothelioma, Malignant 49Mesothelioma 24Lung Neoplasms 18Unspecified Childhood Solid Tumor, Protocol Specific 15Carcinoma, Non-Small-Cell Lung 14Solitary Fibrous Tumor, Pleural 11Pancreatic Neoplasms 11Esophageal Neoplasms 11Sarcoma 10Ovarian Neoplasms 9Small Cell Lung Carcinoma 8Uterine Cervical Neoplasms 7Stomach Neoplasms 7Colonic Neoplasms 7Squamous Cell Carcinoma of Head and Neck 6Retinoblastoma 6Neoplasms 6Carcinoma, Ovarian Epithelial 6Breast Neoplasms 6Thymoma 5Salivary Gland Neoplasms 5Fallopian Tube Neoplasms 5Carcinoma, Hepatocellular 5Astrocytoma 5Urinary Bladder Neoplasms 4Osteosarcoma 4Oligodendroglioma 4Neuroblastoma 4Neoplasm Metastasis 4

Interventions

talazoparib 1Platinum 1Gemcitabine 1Cisplatin 1BAY 1895344 11,2-diaminocyclohexaneplatinum II citrate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Triple Negative Breast Neoplasms × Other solid neoplasm × Clear all
NCT04491942 2026-04-13

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

National Cancer Institute (NCI)

Phase 1 Active not recruiting
74 enrolled
BreastGenitourinaryGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Penile Neoplasms, Triple Negative Breast Neoplasms

NCT02567396 2017-04-24

Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

National Cancer Institute (NCI)

Phase 1 Withdrawn
BreastGastrointestinalGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

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