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Phase

Phase 1 1

Status

Completed 14Recruiting 6Terminated 5Unknown 2Withdrawn 1Active not recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Genitourinary 137Thoracic 22Gynecologic 21Gastrointestinal 21Breast 15Head & Neck 13Dermatologic 13Sarcoma 6Other hematologic neoplasm 4CNS 4Lymphoid 3Plasma cell 2Other solid neoplasm 1NET 1Endocrine 1

Conditions

Advanced Solid Tumor 29Advanced Solid Tumors 20Mesothelioma 19Solid Tumor 18Mesothelioma, Malignant 18Solid Tumors 16Solid Tumor, Adult 11Melanoma 10Carcinoma, Non-Small-Cell Lung 10Ovarian Neoplasms 8Retinoblastoma 7Colorectal Neoplasms 7Carcinoma, Renal Cell 7Uterine Cervical Neoplasms 6Squamous Cell Carcinoma of Head and Neck 6Lung Neoplasms 6Cholangiocarcinoma 6Advanced Malignant Solid Neoplasm 6Triple Negative Breast Neoplasms 5Sarcoma 4Malignant Solid Neoplasm 4Locally Advanced or Metastatic Solid Tumors 4Hematopoietic and Lymphatic System Neoplasm 4Esophageal Neoplasms 4Advanced or Metastatic Solid Tumors 4Stomach Neoplasms 3Small Cell Lung Carcinoma 3Pancreatic Neoplasms 3Neoplasms 3Malignant Solid Tumor 3

Interventions

obinutuzumab 1naptumomab estafenatox 1durvalumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Active not recruiting × Urinary Bladder Neoplasms × Other solid neoplasm × Clear all
NCT03983954 2025-11-28

Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.

NeoTX Therapeutics Ltd.

Phase 1 Active not recruiting
120 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

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