Clinical Trials

Hepatic Impairment

NCT05642611 2026-04-16

ICE COMPRESS

Phase 3 Recruiting

777 enrolled

Malignant Solid Neoplasm

NCT06066424 2026-04-16

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

54 enrolled

Solid Tumors

NCT06082960 2026-04-16

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

45 enrolled

Solid Tumors

NCT06126276 2026-04-16

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

70 enrolled

Malignant Female Reproductive System Neoplasm

NCT06576037 2026-04-16

Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin

128 enrolled

Solid Tumor

NCT06598371 2026-04-16

A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors

141 enrolled

Select Advanced Solid Tumors

NCT06625593 2026-04-16

A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

168 enrolled

Advanced Solid Tumor

NCT07205718 2026-04-16

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

223 enrolled

Advanced or Metastatic Solid Tumors

NCT07266428 2026-04-16

A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients With Advanced Solid Tumors

170 enrolled

Phase NA Not yet recruiting

Advanced Solid Tumors

NCT07278739 2026-04-16

Testing an Educational Program to Improve Goals of Care Conversations Between Patients and Their Care Teams

1,020 enrolled

Malignant Solid Neoplasm

NCT07380334 2026-04-16

A Clinical Study on the Safety, Tolerability, Pharmacokinetics and Efficacy of SHR-1049 in Patients With Advanced Solid Tumors

200 enrolled

Phase 1 Not yet recruiting

Advanced Solid Tumor

NCT07533708 2026-04-16

A Phase I Clinical Study of HLX3902 in Patients With mCRPC and Other Advanced Tumours

48 enrolled

Phase NA Not yet recruiting

mCRPC or Advanced/Metastatic Solid Tumors

NCT07534813 2026-04-16

A Single-Arm Clinical Study of Autologous Tumor-Infiltrating Lymphocyte Injection (GT307) in the Treatment of Metastatic and Recurrent Advanced Solid Tumors

16 enrolled

Advanced Solid Tumors

NCT03736889 2026-04-15

Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors

200 enrolled

MSI-H/dMMR Solid Tumors

NCT04219254 2026-04-15

A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

197 enrolled

Solid Tumor, Adult

NCT04886271 2026-04-15

Recombinant Humanized Anti-CD47 / PD-1 Bifunctional Antibody HX009 Injection in the Treatment of Advanced Solid Tumors

Phase 2 Completed

20 enrolled

CNSGastrointestinalOther solid neoplasmSarcomaThoracic

Advanced Solid Tumor

NCT05275478 2026-04-15

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Phase 1/2 Terminated

110 enrolled

Glioblastoma, Mesothelioma, Sarcoma, Cholangiocarcinoma, Neurofibrosarcoma

NCT05718895 2026-04-15

CLINCH

156 enrolled

Advanced/Metastatic Solid Tumors

NCT06233942 2026-04-15

Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors

308 enrolled

Advanced Solid Tumor

NCT06596473 2026-04-15

A Study of BG-C477 in Participants With Advanced Solid Tumors

310 enrolled

Advanced Solid Tumors

NCT06638931 2026-04-15

ANTARES

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

28 enrolled

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT06741644 2026-04-15

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

660 enrolled

Advanced Solid Tumors

NCT07181681 2026-04-15

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

63 enrolled

Solid Tumors

NCT07226349 2026-04-15

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

105 enrolled

Advanced Solid Tumor

NCT07362888 2026-04-15

First-in-Human Study of ADCE-B05 in Patients With Advanced Solid Tumors

180 enrolled

Solid Tumors (Phase 1)

NCT07395258 2026-04-15

A Study to Test Different Doses of BI 3923948 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

60 enrolled

Solid Tumors

NCT07529535 2026-04-15

A Phase I/II Study of ALK-N001 for Injection in Patients With Advanced Solid Tumors

Phase 1 Suspended

16 enrolled

Advance Solid Tumors

NCT03016156 2026-04-14

Determination of the Sensitivity and Specificity of a Smartphone Application to Detect Retinoblastoma

Phase NA Terminated

1 enrolled

Hydrophthalmos, Retinoblastoma

NCT03447483 2026-04-14

MOTIVATE

Phase NA Completed

150 enrolled

EndocrineNETOther solid neoplasmThoracic

Solid Tumor

NCT04375267 2026-04-14

LuPARP

Phase 1 Completed

18 enrolled

Mesothelioma, Thymoma, Neuroendocrine Tumors

NCT05023486 2026-04-14

NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies

Phase 1/2 Active not recruiting

121 enrolled

Advanced or Metastatic Solid Tumor Malignancies

NCT05071846 2026-04-14

MVX-ONCO-2 in Advanced Solid Tumors

6 enrolled

Solid Tumor, Adult

NCT05155332 2026-04-14

A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

190 enrolled

Solid Tumors

NCT05430373 2026-04-14

GT101 Injection for the Treatment of Metastatic or Recurrent Solid Tumors

31 enrolled

Solid Tumors, Adult

NCT06220864 2026-04-14

SNV1521 in Participants With Advanced Solid Tumors

400 enrolled

Phase 2 Active not recruiting

Advanced Solid Tumor

NCT06351371 2026-04-14

Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Mutations or Fusions (MATCH - Subprotocol K2)

35 enrolled 10 charts

Phase 1/2 Active not recruiting

Malignant Solid Neoplasm

NCT06470763 2026-04-14

EXPAND-1

240 enrolled

Advanced Solid Tumor

NCT06581432 2026-04-14

Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

430 enrolled

Phase 2 Active not recruiting

Solid Tumours

NCT06619509 2026-04-14

A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine

90 enrolled

Solid Tumours

NCT06679634 2026-04-14

Retinoblastoma Phase II Expanded Access Clinical Trial

30 enrolled

Retinoblastoma

NCT06685068 2026-04-14

A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors

Phase 1/2 Terminated

23 enrolled

Advanced Solid Tumor

NCT06718621 2026-04-14

A Study of BL-M08D1 in Patients With Locally Advanced or Metastatic Solid Tumors

22 enrolled

Solid Tumor

NCT01434316 2026-04-13

Veliparib and Dinaciclib in Treating Patients With Advanced Solid Tumors

121 enrolled

Advanced Malignant Solid Neoplasm

NCT02453620 2026-04-13

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

BreastOther solid neoplasm

57 enrolled

Anatomic Stage III Breast Cancer AJCC v8

NCT02535312 2026-04-13

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

Phase 1/2 Active not recruiting

30 enrolled 15 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT04491942 2026-04-13

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

BreastGenitourinaryGynecologicOther solid neoplasmThoracic

74 enrolled

Mesothelioma, Malignant, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Penile Neoplasms, Triple Negative Breast Neoplasms

NCT05879627 2026-04-13

To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors

Phase 1 Terminated

93 enrolled