Announcements Trials
Browse Landscape

Phase

Phase 1 5Phase 1/2 2

Status

Completed 7

Sponsor Class

INDUSTRY 6NIH 1

Study Type

Interventional 7

Sponsor

Cancer Type

Breast 16Gynecologic 8Other solid neoplasm 7Genitourinary 5Gastrointestinal 4Tumor-Agnostic 3Thoracic 3Sarcoma 1Other hematologic neoplasm 1Head & Neck 1Classical hematology 1CNS 1

Conditions

Advanced Solid Tumors 4Solid Tumor 1Advanced Solid Tumor 1Advanced Ovarian Cancer 1

Interventions

pembrolizumab 26Pemetrexed 26Cisplatin 25Nivolumab 22Carboplatin 16Paclitaxel 14Gemcitabine 12Ipilimumab 11tislelizumab 8durvalumab 8Ramucirumab 8Docetaxel 8talazoparib 7Fluorouracil 7Radiotherapy 6Capecitabine 6tremelimumab 5cobimetinib 5atezolizumab 5adavosertib 5Radiosurgery 5Cyclophosphamide 5Bevacizumab 5olaparib 4avelumab 4Temozolomide 4Sunitinib 4Specimen Handling 4Platinum 4PM 01183 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Has results × talazoparib × Other solid neoplasm × Clear all
NCT04497116 2025-10-21

TRESR

Repare Therapeutics

Phase 1/2 Completed
276 enrolled 33 charts
Other solid neoplasm

Advanced Solid Tumor

NCT03077607 2021-06-30

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors

Pfizer

Phase 1 Completed
36 enrolled 28 charts
Other solid neoplasm

Advanced Solid Tumors

NCT02997176 2021-02-25

An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800)

Pfizer

Phase 1 Completed
38 enrolled 42 charts
Other solid neoplasm

Advanced Solid Tumors

NCT01989546 2021-02-23

Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
9 enrolled 11 charts
BreastGynecologicOther solid neoplasm

Advanced Ovarian Cancer

NCT02997163 2021-01-05

An Open-Label Pharmacokinetics and Safety Study of Talazoparib

Pfizer

Phase 1 Completed
34 enrolled 39 charts
Other solid neoplasm

Advanced Solid Tumors

NCT03042910 2019-12-17

A Study to Assess the Effects of Talazoparib on Cardiac Repolarization in Patients With Advanced Solid Tumors

Pfizer

Phase 1 Completed
38 enrolled 24 charts
Other solid neoplasm

Solid Tumor

NCT03070548 2018-12-17

A Study of Talazoparib in Patients With Advanced Solid Tumors

Pfizer

Phase 1 Completed
6 enrolled 34 charts
Other solid neoplasm

Advanced Solid Tumors

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