Clinical Trials Browser

Phase 2 × Has results × Other solid neoplasm × Clear all

NCT06360588 2026-04-17

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Loss (MATCH - Subprotocol Z1G)

Phase 2 Active not recruiting

22 enrolled 9 charts

Other solid neoplasm

Malignant Solid Neoplasm

NCT06351371 2026-04-14

Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Mutations or Fusions (MATCH - Subprotocol K2)

Phase 2 Active not recruiting

35 enrolled 10 charts

Other solid neoplasm

Malignant Solid Neoplasm

NCT06136897 2026-04-13

Testing Trastuzumab and Pertuzumab in Patients With Higher Than Normal Copies of the HER2 Gene Found in Their Tumors (MATCH - Subprotocol J)

Phase 2 Active not recruiting

35 enrolled 10 charts

Other solid neoplasm

Malignant Solid Neoplasm

NCT04083976 2026-03-19

RAGNAR

Phase 2 Active not recruiting

316 enrolled 15 charts

Other solid neoplasm

Advanced Solid Tumor

NCT01843374 2026-03-05

Tremelimumab

Phase 2 Active not recruiting

571 enrolled 19 charts

Other solid neoplasmThoracic

Diabetes Mellitus, Insulin-Dependent, 12, Mesothelioma, Malignant

NCT04999969 2026-02-03

Safety, Pharmacokinetics and Clinical Activity of AZD0171 in Combination With Durvalumab and Chemotherapy in Locally Advanced or Metastatic Solid Tumours

Phase 2 Active not recruiting

126 enrolled 30 charts

Other solid neoplasm

Locally Advanced or Metastatic Solid Tumours

NCT04504942 2026-01-23

Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors

Phase 2 Completed

16 enrolled 16 charts

Other solid neoplasm

Solid Tumor, Adult

NCT05388058 2026-01-16

Topical Cannabidiol for the Treatment of Chemotherapy-Induced Peripheral Neuropathy

Phase 2 Completed

40 enrolled 15 charts

OtherOther solid neoplasm

Chemotherapy-Induced Peripheral Neuropathy

NCT03075527 2026-01-08

A Phase 2 Study of Durvalumab in Combination With Tremelimumab in Malignant Pleural Mesothelioma

Phase 2 Terminated

19 enrolled 12 charts

Other solid neoplasmThoracic

Mesothelioma

NCT05005429 2025-12-23

BIMES

Phase 2 Completed

47 enrolled 9 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT02611037 2025-12-18

Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma

Phase 2 Completed

34 enrolled 12 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT02060188 2025-11-06

CheckMate142

Phase 2 Completed

385 enrolled 17 charts 4 FDA

GastrointestinalOther solid neoplasm

Microsatellite Unstable Colorectal Cancer

NCT04914897 2025-10-02

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)

Phase 2 Terminated

106 enrolled 21 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT05014828 2025-08-24

To Evaluate the Efficacy and Safety of Tislelizumab in Combination With Lenvatinib in Participants With Selected Solid Tumors

Phase 2 Completed

58 enrolled 16 charts

Other solid neoplasm

Advanced Solid Tumor

NCT04671901 2025-05-28

A Study of Romiplostim to Prevent Low Platelet Counts in Children and Young Adults Receiving Chemotherapy for Solid Tumors

Phase 2 Terminated

2 enrolled 4 charts

Other solid neoplasm

Solid Tumor

NCT04171219 2025-05-16

Talabostat and Pembrolizumab for the Treatment of Advanced Solid Cancers

Phase 2 Terminated

31 enrolled 15 charts

Other solid neoplasm

Advanced Malignant Solid Neoplasm

NCT04082572 2025-05-13

Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers

Phase 2 Completed

35 enrolled 10 charts

Other solid neoplasm

Locally Advanced Malignant Solid Neoplasm

NCT04827576 2025-05-08

ELEVATELung&UC

Phase 2 Terminated

106 enrolled 22 charts

Other solid neoplasm

Solid Tumor

NCT04716634 2025-03-25

Efficacy and Safety of Tislelizumab in Combination With Fruquintinib in Participants With Selected Solid Tumors

Phase 2 Completed

84 enrolled 17 charts

Other solid neoplasm

Advanced Solid Tumors

NCT03477175 2025-01-07

Study to Assess the Long-term Safety of Lenvatinib Monotherapy, a Lenvatinib Combination Regimen, or a Comparator Treatment Arm to Cancer Participants in Eisai Sponsored Lenvatinib Trials

Phase 2 Completed

40 enrolled 13 charts

Other solid neoplasm

Solid Tumors

NCT01265433 2024-10-09

Galinpepimut-S (WT-1 Analog Peptide) Vaccine in Malignant Pleural Mesothelioma After Combined Modality Therapy

Phase 2 Completed

41 enrolled 12 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT03802123 2024-07-09

iCorrelate

Phase 2 Completed

52 enrolled 39 charts

Other solid neoplasm

Positron-Emission Tomography

NCT04488003 2024-06-04

Study of Ulixertinib for Patients With Advanced Malignancies Harboring MEK or Atypical BRAF Alterations

Phase 2 Terminated

104 enrolled 13 charts

Other solid neoplasm

Advanced Solid Tumor

NCT03502746 2024-05-14

Phase II Nivolumab and Ramucirumab for Patients With Previously-Treated Mesothelioma

Phase 2 Terminated

34 enrolled 11 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Phase 2 Completed

78 enrolled 11 charts

CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

NCT03461952 2024-02-22

NIMBLe

Phase 2 Terminated

4 enrolled 4 charts

Other solid neoplasm

Advanced Solid Tumors

NCT02004028 2024-02-20

Window of Opportunity Study of VS-6063 (Defactinib) in Surgical Resectable Malignant Pleural Mesothelioma Participants

Phase 2 Terminated

35 enrolled 15 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Adenoma, Mesothelioma, Neoplasms, Mesothelial

NCT03834220 2024-02-07

Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)

Phase 2 Terminated

63 enrolled 18 charts

Other solid neoplasm

Solid Tumor

NCT04071756 2024-02-07

Topical Tazarotene Vs Placebo In Hand-Foot-Skin Reactions

Phase 2 Terminated

8 enrolled 12 charts

Other solid neoplasm

Solid Tumor

NCT05041062 2024-01-03

A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal Mesothelioma

Phase 2 Completed

2 enrolled 8 charts

Other solid neoplasmThoracic

Lung Neoplasms, Mesothelioma

NCT01190644 2023-11-29

Study to Evaluate Effect of a Single Dose of Sotatercept (ACE-011) on Red Blood Cell Mass and Plasma Volume in Participants With Solid Tumors

Phase 2 Terminated

5 enrolled 11 charts

Other solid neoplasm

Solid Tumors

NCT03274661 2023-10-19

Pembrolizumab Activity in Patients With Homologous Recombination Competent and Deficient Tumors

Phase 2 Completed

52 enrolled 12 charts

Other solid neoplasm

Solid Tumor, Adult

NCT03253679 2023-10-17

AZD1775 in Treating Patients With Advanced Refractory Solid Tumors With CCNE1 Amplification

Phase 2 Completed

31 enrolled 13 charts

Other solid neoplasm

Advanced Malignant Solid Neoplasm

NCT01827384 2023-09-29

MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene Variations

Phase 2 Completed

208 enrolled 27 charts

Other solid neoplasm

Advanced Malignant Solid Neoplasm

NCT03207347 2023-09-15

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

Phase 2 Completed

37 enrolled 15 charts

DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

Uveal Melanoma, Carcinoma, Renal Cell, Mesothelioma, Cholangiocarcinoma

NCT03926143 2023-08-04

A Clinical Study of Anetumab Ravtansine in Adults With Solid Tumors Who Have Been Treated in Previous Bayer-sponsored Anetumab Ravtansine Studies

Phase 2 Terminated

9 enrolled 10 charts

Other solid neoplasmThoracic

Mesothelioma

NCT02899195 2023-07-05

PrE0505

Phase 2 Completed

55 enrolled 13 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT00101283 2023-07-03

Pemetrexed Plus Gemcitabine or Carboplatin for Patients With Advanced Malignant Pleural Mesothelioma

Phase 2 Completed

32 enrolled 8 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT02426892 2023-04-18

Nivolumab and HPV-16 Vaccination in Patients With HPV-16 Positive Incurable Solid Tumors

Phase 2 Completed

33 enrolled 14 charts

Other solid neoplasm

Solid Tumors

NCT02454972 2023-03-02

Clinical Trial of Lurbinectedin (PM01183) in Selected Advanced Solid Tumors

Phase 2 Completed

345 enrolled 34 charts 3 FDA

Other solid neoplasm

Advanced Solid Tumors

NCT02293005 2022-10-04

Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma

Phase 2 Completed

28 enrolled 11 charts

Other solid neoplasmThoracic

Lung Neoplasms, Mesothelioma

NCT02592551 2022-09-29

MEDI4736 Or MEDI4736 + Tremelimumab In Surgically Resectable Malignant Pleural Mesothelioma

Phase 2 Completed

24 enrolled 22 charts

Other solid neoplasmThoracic

Mesothelioma

NCT00738582 2022-09-22

Amatuximab

Phase 2 Completed

89 enrolled 12 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT01515306 2022-03-08

A Study of Ramucirumab (IMC-1121B) and Paclitaxel in Participants With Solid Tumors

Phase 2 Completed

48 enrolled 17 charts

Other solid neoplasm

Malignant Solid Tumor

NCT03220854 2022-01-10

SBRT + PD-1/PDL-1 Inhibiting Therapy for Advanced Solid Tumors After Dz Control on PD-1/PDL-1 Tx

Phase 2 Completed

5 enrolled 12 charts

Other solid neoplasm

Solid Tumor

NCT02568449 2021-12-09

Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent

Phase 2 Completed

20 enrolled 11 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT03644550 2021-12-02

Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma

Phase 2 Terminated

18 enrolled 15 charts

Other solid neoplasmThoracic

Mesothelioma

NCT01085630 2021-08-18

Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapy

Phase 2 Completed

72 enrolled 12 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT01457118 2021-07-12

An Extension Study of NKTR-102 in Cancer Patients Previously Enrolled in NKTR-102 Studies

Phase 2 Completed

27 enrolled 18 charts

Other solid neoplasm

Malignant Solid Tumor

NCT03264066 2021-05-11

A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid Tumors

Phase 2 Completed

87 enrolled 24 charts

Other solid neoplasm

Solid Tumors