Clinical Trials Browser

NCT06509906 2025-12-18

M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)

Phase 1 Terminated

3 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT06006273 2025-11-10

A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors

Phase 1 Recruiting

48 enrolled

Other solid neoplasm

Refractory Solid Tumors

NCT05978492 2025-04-24

A Study of TXN10128 in Subjects With Solid Tumors

Phase 1 Recruiting

96 enrolled

Other solid neoplasm

Locally Advanced (Unresectable) or Metastatic Solid Tumors

NCT06760117 2025-01-06

UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors

Phase 1 Recruiting

39 enrolled

Other solid neoplasm

Pediatric Solid Tumor

NCT05620862 2024-07-09

Phase I Dose Escalation and Pharmacokinetics Clinical Trial of Mitoxantrone Hydrochloride Liposome in Children With Relapsed and Refractory Lymphoma and Solid Tumors

Phase 1 Active not recruiting

68 enrolled

Other solid neoplasm

Pediatric Solid Tumor

NCT00993044 2023-10-06

VIT-B

Phase 1 Completed

13 enrolled 6 charts

Other solid neoplasm

Refractory Solid Tumors in Children

NCT02588105 2022-09-19

AToM

Phase 1 Completed

84 enrolled

Other solid neoplasm

Advanced Solid Tumours

NCT02250157 2022-02-22

A Dose-regimen Finding Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oratecan in Subjects With Advanced Malignancies

Phase 1 Completed

35 enrolled

Other solid neoplasm

Solid Tumor

NCT02596503 2022-02-15

A Study of Eribulin in Combination With Oral Irinotecan for Adolescent and Young Adult Patients With Relapsed or Refractory Solid Tumors

Phase 1 Completed

2 enrolled

Other solid neoplasm

Relapsed Solid Tumors

NCT03318445 2021-03-04

Rucaparib and Irinotecan in Cancers With Mutations in DNA Repair

Phase 1 Completed

22 enrolled

Other solid neoplasm

Solid Tumor, Unspecified, Adult

NCT00786669 2021-02-10

VITAC

Phase 1 Completed

13 enrolled

Other solid neoplasm

Solid Tumor

NCT02392793 2021-02-09

Talazoparib Plus Irinotecan With or Without Temozolomide in Children With Refractory or Recurrent Solid Malignancies

Phase 1 Completed

43 enrolled

Other solid neoplasm

Childhood Solid Tumors

NCT04689100 2020-12-30

Efficacy and Safety of JMT101 in Patients With Advanced Solid Tumor

Phase 1 Unknown

259 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT02157792 2020-04-01

M6620 First in Human Study

Phase 1 Completed

200 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT00002902 2019-03-13

Irinotecan Plus ICI D1694 in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00215501 2018-11-02

Capecitabine or 5-Fluorouracil in Combination With Irinotecan and Cisplatin in Patients With Solid Tumor Malignancies

Phase 1 Completed

54 enrolled

Other solid neoplasm

Solid Tumor

NCT03503604 2018-04-20

A Study of Anti-VEGF Monoclonal Antibody hPV19 in Patients With Solid Tumors

Phase 1 Unknown

18 enrolled

Other solid neoplasm

Solid Tumors

NCT01009073 2017-11-20

A Study Evaluating ABT-263 With Erlotinib, ABT-263 With Irinotecan, and ABT-263 Monotherapy in Cancer Subjects

Phase 1 Completed

51 enrolled

Other solid neoplasm

Solid Tumors

NCT00861328 2017-06-23

Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin

Phase 1 Completed

18 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT00186979 2017-04-26

Study of ZD1839 Combined With Irinotecan and Vincristine in Pediatric Patients With Refractory Solid Tumors

Phase 1 Completed

34 enrolled

Other solid neoplasm

Solid Tumors

NCT00731276 2017-03-31

Irinotecan in Treating Asian Patients With Solid Tumors

Phase 1 Completed

18 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00026195 2016-07-06

Irinotecan in Treating Aging Patients With Solid Tumors

Phase 1 Completed

140 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00547547 2015-11-06

High-Selenium Brassica Juncea, Irinotecan, and Capecitabine in Treating Patients With Advanced Cancer

Phase 1 Completed

22 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT02395068 2015-08-19

Pharmacokinetics Study of Nimotuzumab in Patients With Solid Tumors

Phase 1 Unknown

40 enrolled

Other solid neoplasm

Solid Tumors

NCT00020488 2015-04-30

Combination Chemotherapy in Treating Patients Who Have Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT01463982 2015-04-23

Phase I of OratecanTM in Combination With Capecitabine in Patients With Advanced Solid Malignancies

Phase 1 Completed

21 enrolled 10 charts

Other solid neoplasm

Solid Tumor

NCT00008424 2014-05-05

Irinotecan in Treating Children With Refractory or Advanced Solid Tumors Who Are Receiving Anticonvulsants

Phase 1 Completed

7 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT01141244 2014-04-10

Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Phase 1 Completed

72 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00046917 2014-02-24

Combination Chemotherapy in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

13 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00006095 2014-02-21

Combination Chemotherapy in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

Phase 1 Completed

20 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00054288 2014-01-13

Irinotecan and Gemcitabine in Treating Patients With Refractory Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00112892 2014-01-13

Irinotecan and Selenium in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

36 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00004051 2013-12-19

Irinotecan in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

40 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00005791 2013-12-19

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00021073 2013-12-11

Combination Chemotherapy in Treating Patients With Advanced Cancer

Phase 1 Completed

90 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00002939 2013-09-05

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer

Phase 1 Completed

21 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00004919 2013-07-02

Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

Phase 1 Completed

30 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00016861 2013-06-26

Irinotecan in Treating Children With Refractory or Progressive Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00003742 2013-06-21

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00074321 2013-06-06

Irinotecan, Oxaliplatin, and Capecitabine in Treating Patients With Unresectable Solid Tumors

Phase 1 Completed

84 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00042874 2013-06-04

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

77 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00119236 2013-06-04

17-AAG and Irinotecan in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

48 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003711 2013-05-30

Combination Chemotherapy in Treating Patients With Metastatic Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00084877 2013-05-16

Irinotecan and 3-AP in Treating Patients With Metastatic or Unresectable Solid Tumors

Phase 1 Completed

36 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003109 2013-04-17

Irinotecan Plus Raltitrexed in Treating Patients With Refractory Solid Tumors

Phase 1 Completed

39 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00024284 2013-04-05

Carboplatin and Irinotecan in Treating Children With Refractory Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00006000 2013-01-31

SU5416, Irinotecan, and Cisplatin in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00079352 2013-01-25

Flavopiridol, Gemcitabine, and Irinotecan in Treating Patients With Unresectable or Metastatic Solid Tumors

Phase 1 Completed

24 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00062127 2013-01-24

Irinotecan and Thalidomide in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

35 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003710 2012-08-09

Irinotecan Plus Mitomycin in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

12 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific