Clinical Trials Browser

Interventional × Midazolam × Other solid neoplasm × Clear all

NCT03600883 2026-03-16

A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)

Phase 1/2 Active not recruiting

713 enrolled 1 FDA

Other solid neoplasm

KRAS p.G12C Mutant Advanced Solid Tumors

NCT04973163 2026-02-17

A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors, KRAS Mutation

NCT01585623 2025-03-05

Drug Interaction Study of SAR302503 in Patients With Solid Tumor

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT04887194 2024-05-08

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Phase 1 Completed

Other solid neoplasm

Advanced Solid Tumor

NCT06348290 2024-04-04

Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Phase 1 Unknown

Other solid neoplasm

Solid Tumor, Adult

NCT04958226 2024-01-25

A Study to Assess the Effect of Capivasertib on Midazolam in Patients With Advanced Solid Tumours

Phase 1 Completed

Other solid neoplasm

Solid Tumour

NCT01655225 2022-04-08

A Study of LY3023414 in Participants With Advanced Cancer

Phase 1 Completed

BreastLymphoidOther solid neoplasmThoracic

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Lymphoma, Non-Hodgkin, Mesothelioma, Neoplasm Metastasis

NCT04187456 2021-08-19

A Study in Healthy Male Subjects to Understand How Savolitinib When Taken With Midazolam Behaves Inside the Body

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT02520752 2020-12-10

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

cMET-dysregulated Advanced Solid Tumors

NCT03333824 2019-03-25

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Phase 1 Completed

Other solid neoplasm

Solid Tumours

NCT03330990 2018-08-21

Evaluate the Effect of Entrectinib on the Pharmacokinetics of Midazolam in Cancer Patients

Phase 1 Completed

Other solid neoplasm

Advanced Solid Tumor

NCT00467779 2016-08-26

Study of Cobimetinib in Participants With Solid Tumors

Phase 1 Completed

119 enrolled 63 charts

Other solid neoplasm

Solid Tumor

NCT00808184 2012-11-01

Pharmacokinetic Study of CPT-11, Raltegravir and Midazolam With Characterisation of UGT1A1 Genotype

Phase 4 Completed

Other solid neoplasm

Solid Tumor