Clinical Trials

Advanced Solid Tumors

NCT07381829 2026-02-02

A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combined With Chemotherapy in Lung Cancer

Phase 1 Recruiting

328 enrolled

Advanced Solid Tumor Cancer

NCT03760575 2025-12-04

Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

Phase 1 Recruiting

20 enrolled

Mesothelioma, Malignant

NCT05117476 2025-11-24

MICA

440 enrolled

Advanced Solid Tumor

NCT03228537 2025-11-10

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

28 enrolled 17 charts

Mesothelioma, Malignant

NCT04185883 2025-10-22

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

Other solid neoplasmSarcoma

610 enrolled

Advanced Solid Tumors

NCT04162015 2025-09-12

A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma

22 enrolled

Mesothelioma, Malignant

NCT04047862 2025-08-22

Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors

446 enrolled 49 charts

Locally Advanced and Metastatic Solid Tumors

NCT04153565 2025-07-17

MK-3475-A17

19 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma

NCT02707666 2024-07-31

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

7 enrolled

Mesothelioma, Malignant

NCT06116240 2023-11-03

A Clinical Trial of TQB2450 Injection Combined With AL2846 Capsules in Patients With Advanced Solid Tumors

Phase 1 Unknown

135 enrolled

Solid Tumor

NCT03023319 2022-06-14

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

GenitourinaryGynecologicOther solid neoplasmThoracic

6 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Mesothelioma, Ovarian Neoplasms, Thymoma, Thymus Neoplasms

NCT04173338 2022-06-14

Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma

GenitourinaryOther solid neoplasmThoracic

9 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell

NCT01655225 2022-04-08

A Study of LY3023414 in Participants With Advanced Cancer

BreastLymphoidOther solid neoplasmThoracic

156 enrolled

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Lymphoma, Non-Hodgkin, Mesothelioma, Neoplasm Metastasis

NCT02838745 2022-03-31

Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPM

7 enrolled

Mesothelioma

NCT01675765 2020-09-30

Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma

60 enrolled 15 charts

Mesothelioma, Malignant, Neoplasms

NCT03920839 2020-04-24

INCMGA00012 Plus Chemotherapy in Participants With Advanced Solid Tumors (POD1UM-105)

Phase 1 Withdrawn

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT02639091 2019-11-07

Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors

36 enrolled

Lung Neoplasms, Mesothelioma

NCT00390000 2019-04-08

Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors

29 enrolled

Unspecified Adult Solid Tumor, Protocol Specific

NCT01215916 2019-03-15

A Phase 1 Study in Patients With Solid Tumors

39 enrolled 18 charts

Solid Tumors

NCT01445392 2018-08-03

SS1(dsFV)PE38 Plus Pemetrexed and Cisplatin to Treat Malignant Pleural Mesothelioma

24 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT00703638 2017-11-29

Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

16 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Mesothelioma, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT02639767 2016-12-07

Concurrent Pemetrexed/Cisplatin With Pleural Intensity Modulated Radiation Therapy for Patients With Unresectable Malignant Pleural Mesothelioma

Phase 1 Withdrawn

Mesothelioma, Malignant

NCT01450384 2016-02-23

Pemetrexed Disodium and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors

37 enrolled

Unspecified Adult Solid Tumor

NCT00402766 2015-11-18

Cisplatin, Pemetrexed, and Imatinib Mesylate in Malignant Mesothelioma

19 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT01170871 2014-05-21

Ixabepilone and Pemetrexed/Solid Tumors

Phase 1 Withdrawn

Advanced Solid Tumors

NCT00070473 2014-02-20

Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors

33 enrolled

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00003711 2013-05-30

Combination Chemotherapy in Treating Patients With Metastatic Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003706 2012-06-28

LY231514 in Treating Patients With Locally Advanced or Metastatic Solid Tumors and Varying Degrees of Kidney Function

50 enrolled

Unspecified Adult Solid Tumor, Protocol Specific

NCT00320073 2012-05-16

Vinflunine and Erlotinib or Pemetrexed in Treating Patients With Unresectable or Metastatic Solid Tumors

41 enrolled

Unspecified Adult Solid Tumor, Protocol Specific

NCT00573690 2012-04-24

Sorafenib Combined With Cisplatin and Etoposide or Carboplatin and Pemetrexed in Treating Patients With Metastatic Solid Tumors

31 enrolled

Unspecified Adult Solid Tumor, Protocol Specific

NCT00502567 2011-07-27

A Study to Assess Safety, Tolerability and PK of AZD2171 and Chemotherapy on Patients With Solid Tumors

104 enrolled

Advanced Solid Tumor

NCT00528619 2011-04-08

A Study To Find The Best Dose Of SU011248 When Given With Pemetrexed, Pemetrexed And Cisplatin Or Pemetrexed And Carboplatin In Patients With Advanced Solid Tumors

96 enrolled