Clinical Trials

Phase 2 Not yet recruiting

Advanced Solid Tumors

NCT07415031 2026-04-08

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

170 enrolled

Solid Tumors

NCT04665206 2026-04-02

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

Phase 1/2 Recruiting

434 enrolled

Mesothelioma

NCT06097728 2026-04-02

eVOLVE-Meso

Phase 3 Recruiting

825 enrolled

Phase 1 Active not recruiting

Mesothelioma, Malignant, Mesothelioma

NCT04328844 2026-03-30

A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

210 enrolled

DermatologicLymphoidMyeloidOther solid neoplasmThoracic

Uveal Melanoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mesothelioma, Primary Myelofibrosis

NCT07098988 2026-02-27

Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

Phase 2 Recruiting

107 enrolled

Metastatic Non-Squamous Non-Small Cell Lung Cancer

NCT05067283 2026-02-12

KANDLELIT-001

Phase 1 Recruiting

830 enrolled

Advanced Solid Tumors

NCT06783647 2026-02-12

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]

Phase 2 Recruiting

230 enrolled

Advanced Solid Tumour

NCT07381829 2026-02-02

A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combined With Chemotherapy in Lung Cancer

Phase 1 Recruiting

328 enrolled

Advanced Solid Tumor Cancer

NCT05136677 2026-01-23

CheckMate 6DW

102 enrolled

Phase 1 Active not recruiting

Mesothelioma, Malignant

NCT05117476 2025-11-24

MICA

440 enrolled

Phase 1 Active not recruiting

Advanced Solid Tumor

NCT04185883 2025-10-22

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

610 enrolled

Other solid neoplasmSarcoma

Advanced Solid Tumors

NCT06385678 2025-09-19

A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Phase 1/2 Active not recruiting

47 enrolled

Phase 1/2 Not yet recruiting

Advanced KRAS G12D Mutant Solid Tumors

NCT07157956 2025-09-05

CVL006-T1002

318 enrolled

Advanced Solid Tumor

NCT04047862 2025-08-22

Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors

446 enrolled 49 charts

Locally Advanced and Metastatic Solid Tumors

NCT04153565 2025-07-17

MK-3475-A17

19 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma

NCT04843007 2024-10-23

Alvopem® (Pemetrexed) Safety Assessment

Completed

199 enrolled 21 charts

605 enrolled 17 charts 3 FDA

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT02899299 2024-05-21

CheckMate743

Phase 3 Completed

Mesothelioma

NCT06116240 2023-11-03

A Clinical Trial of TQB2450 Injection Combined With AL2846 Capsules in Patients With Advanced Solid Tumors

Phase 1 Unknown

135 enrolled

Solid Tumor

NCT02709512 2023-10-04

ATOMIC

Phase 2/3 Completed

249 enrolled 17 charts

Mesothelioma, Malignant, Mesothelioma

NCT05794477 2023-06-02

A Study of SHR-1802 in Combination With Adebrelimab in Patients With Advanced Solid Tumors

Phase 1/2 Unknown

132 enrolled

Advanced Solid Tumor

NCT00738582 2022-09-22

Amatuximab

89 enrolled 12 charts

Mesothelioma, Malignant

NCT02347917 2022-04-12

A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma

Phase 1/2 Completed

28 enrolled 23 charts

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT01655225 2022-04-08

A Study of LY3023414 in Participants With Advanced Cancer

BreastLymphoidOther solid neoplasmThoracic

156 enrolled

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Lymphoma, Non-Hodgkin, Mesothelioma, Neoplasm Metastasis

NCT00700336 2021-07-20

Study of CBP501 + Pemetrexed + Cisplatin on MPM (Phase I/II)

Phase 1/2 Completed

69 enrolled 9 charts

Mesothelioma, Malignant

NCT01675765 2020-09-30

Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma

60 enrolled 15 charts

Mesothelioma, Malignant, Neoplasms

NCT03920839 2020-04-24

INCMGA00012 Plus Chemotherapy in Participants With Advanced Solid Tumors (POD1UM-105)

Phase 1 Withdrawn

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT02357147 2020-03-17

ARTEMIS

Phase 2 Terminated

124 enrolled 10 charts

Severe combined immunodeficiency with sensitivity to ionizing radiation, Mesothelioma, Malignant

NCT02639091 2019-11-07

Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors

36 enrolled

Lung Neoplasms, Mesothelioma

NCT01907100 2019-03-18

Nintedanib (BIBF 1120) in Mesothelioma

Phase 2/3 Terminated

545 enrolled 15 charts

Mesothelioma

NCT01215916 2019-03-15

A Phase 1 Study in Patients With Solid Tumors

39 enrolled 18 charts

Solid Tumors

NCT02397928 2018-09-25

Safety and Efficacy of TTFields (150 kHz) Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma (STELLAR)

82 enrolled

Mesothelioma, Malignant

NCT01139775 2018-05-18

A Study in Non Small Cell Lung Cancer

Phase 1/2 Completed

76 enrolled 24 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung, Mesothelioma

NCT00502567 2011-07-27

A Study to Assess Safety, Tolerability and PK of AZD2171 and Chemotherapy on Patients With Solid Tumors

104 enrolled

Advanced Solid Tumor

NCT00528619 2011-04-08

A Study To Find The Best Dose Of SU011248 When Given With Pemetrexed, Pemetrexed And Cisplatin Or Pemetrexed And Carboplatin In Patients With Advanced Solid Tumors

96 enrolled

Carcinoma, Non-Small-Cell Lung, Mesothelioma, Neoplasms

NCT00316225 2010-07-09

Study of Pemetrexed in Mesothelioma and Lung Cancer Patients With Fluid Around the Lungs or Abdomen

31 enrolled 18 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Mesothelioma

NCT00386815 2007-04-11

Safety Confirmation Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesothelioma

20 enrolled

Mesothelioma, Malignant

NCT00040625 2007-03-15

ALIMTA (Pemetrexed) Alone or in Combination With Cisplatin for Patients With Malignant Mesothelioma.

Approved for marketing

Mesothelioma

NCT00061477 2007-01-26

Pemetrexed Plus Gemcitabine as Front-Line Chemotherapy for Patients With Malignant Pleural or Peritoneal Mesothelioma

48 enrolled

Mesothelioma

NCT00190762 2007-01-26

A Study Comparing Pemetrexed Plus Best Supportive Care Versus Best Supportive Care Alone in the Treatment of Mesothelioma

Phase 3 Completed

240 enrolled