Clinical Trials Browser

Topotecan × Other solid neoplasm × Clear all

NCT05521984 2026-04-02

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Phase 1 Recruiting

Other solid neoplasm

Pediatric Brain Tumor

NCT04681417 2025-11-28

RETINO 2018

Phase 2/3 Recruiting

Other solid neoplasm

Retinoblastoma

NCT00186888 2025-09-04

Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma

Phase 3 Completed

107 enrolled 34 charts

Other solid neoplasm

Eye Neoplasms, Retinoblastoma, Retinal Neoplasms

NCT06972602 2025-05-15

High-dose Topotecan for Retinoblastoma With Recurrent or Refractory Vitreous Seed

Phase EARLY_PHASE1 Recruiting

Other solid neoplasm

Recurrence, Retinoblastoma

NCT01783535 2024-04-16

Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

Phase 2 Active not recruiting

Other solid neoplasm

Retinoblastoma

NCT04455139 2023-10-03

EuRbG2018

Phase 2 Terminated

Other solid neoplasm

Retinoblastoma

NCT02303028 2022-06-28

TOPAZ

Phase 1/2 Completed

Other solid neoplasm

Solid Tumors

NCT03987685 2022-02-16

Evaluate Oral Topotecan With HM30181A Monotherapy in Patients With Advanced Malignancies

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT04799002 2021-03-16

Topotecan and Melphalan for Retinoblastoma

Phase 3 Recruiting

Other solid neoplasm

Retinoblastoma

NCT00002950 2020-08-17

Topotecan Plus Sargramostim in Treating Patients With Advanced Cancer

Phase 1/2 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT02390843 2020-04-03

AflacST1402

Phase 1 Completed

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

NCT00003194 2019-04-05

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors

Phase 1 Terminated

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00732420 2017-11-13

Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumours

NCT01593228 2017-09-19

Treatment Extension Study for Patients Who Have Previously Participated and Have Benefited From Iniparib in a Clinical Trial

Phase 3 Completed

Other solid neoplasm

Solid Tumors

NCT00541359 2017-08-09

Bortezomib and Topotecan Hydrochloride in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00980551 2017-03-03

RELRB1

Phase NA Withdrawn

Other solid neoplasm

Retinoblastoma

NCT00682279 2015-04-17

A Phase I Study Of Oral Topotecan And Lapatinib In Subjects With Advanced Solid Tumors

Phase 1 Withdrawn

Other solid neoplasm

Advanced Solid Tumors

NCT00002948 2014-07-02

High-Dose Topotecan and Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Phase 1 Terminated

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00004979 2014-01-06

Topotecan and Paclitaxel in Treating Patients With Advanced Non-small Cell Lung Cancer or Other Advanced Solid Tumors

Phase 1/2 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003198 2013-06-27

Ifosfamide and Topotecan in Treating Patients With Refractory Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00002515 2013-06-24

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Phase 2 Completed

CNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther solid neoplasmSarcoma

Testicular Germ Cell Tumor, Burkitt Lymphoma, Chondrosarcoma, Fibrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Sarcoma, Osteosarcoma, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Dendritic Cell Sarcoma, Interdigitating, Desmoplastic Small Round Cell Tumor

NCT00002587 2013-06-03

Paclitaxel Plus Topotecan in Treating Patients With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00068484 2013-02-01

A Dose Finding Phase I Trial of the Combination of Topotecan and PS-341, a Novel Proteasome Inhibitor, in Advanced Malignancies

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00005990 2012-11-09

R115777 Plus Topotecan in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00502892 2012-08-01

Topotecan, Ifosfamide and Carboplatin in Children and Young Adults With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT00004006 2011-10-04

Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma

Phase 2 Completed

Other solid neoplasm

Retinoblastoma

NCT00516438 2010-12-08

Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Topotecan

Phase 1 Completed

Other solid neoplasm

Malignant Solid Tumors

NCT00628732 2009-01-28

A Pharmacokinetic Study of Oral Cyclophosphamide and Topotecan in Children With Recurrent Solid Tumors

Phase 2 Completed

Other solid neoplasm

Solid Tumors

NCT00460876 2008-05-02

Phase I Trial of Periocular Topotecan in Retinoblastoma

Phase 1 Completed

Other solid neoplasm

Retinoblastoma