Announcements Trials
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Phase

Phase 1 4

Status

Completed 4

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 23Other solid neoplasm 4Gastrointestinal 2Dermatologic 2CNS 2Tumor-Agnostic 1Sarcoma 1Head & Neck 1Breast 1

Conditions

cMET-dysregulated Advanced Solid Tumors 2cMET Dysegulation Advanced Solid Tumors 1Advanced Solid Tumor 1

Interventions

Injections 98pembrolizumab 90Carboplatin 57Paclitaxel 54Cisplatin 52Nivolumab 44Docetaxel 43Pemetrexed 42Gemcitabine 37atezolizumab 32tislelizumab 29Bevacizumab 29toripalimab 23Fluorouracil 23Capecitabine 23Irinotecan 22Oxaliplatin 20durvalumab 19Ipilimumab 18Leucovorin 17Cetuximab 17Rifampin 14Itraconazole 14olaparib 13spartalizumab 12Midazolam 12Cyclophosphamide 12trifluridine tipiracil drug combination 11sintilimab 11Drug Therapy 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
INDUSTRY × capmatinib × Other solid neoplasm × Clear all
NCT01546428 2020-12-19

A Phase I Study of INC280 in Japanese Patients With Advanced Solid Tumors

Novartis

Phase 1 Completed
44 enrolled
Other solid neoplasm

Advanced Solid Tumor

NCT02925104 2020-12-19

A Dose Escalation Study to Assess PK, Safety and Tolerability of INC280 When Taken With Food in cMET Dysregulated Advanced Solid Tumors.

Novartis

Phase 1 Completed
36 enrolled
Other solid neoplasm

cMET Dysegulation Advanced Solid Tumors

NCT02520752 2020-12-10

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

Novartis

Phase 1 Completed
37 enrolled
Other solid neoplasm

cMET-dysregulated Advanced Solid Tumors

NCT02626234 2020-12-10

A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors

Novartis

Phase 1 Completed
32 enrolled
Other solid neoplasm

cMET-dysregulated Advanced Solid Tumors

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