Announcements Trials
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Phase

Phase 1 4

Status

Completed 4

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 23Sarcoma 4Other solid neoplasm 4Gastrointestinal 4CNS 4Tumor-Agnostic 3Dermatologic 3Other hematologic neoplasm 2Genitourinary 2Breast 2Lymphoid 1Head & Neck 1

Conditions

cMET-dysregulated Advanced Solid Tumors 2cMET Dysegulation Advanced Solid Tumors 1Advanced Solid Tumor 1

Interventions

Cisplatin 145pembrolizumab 129Carboplatin 125Injections 108Pemetrexed 97Paclitaxel 97Gemcitabine 85Irinotecan 75Nivolumab 71Cyclophosphamide 71Docetaxel 68Bevacizumab 57Oxaliplatin 49Fluorouracil 48atezolizumab 46Capecitabine 46Etoposide 42Leucovorin 41tislelizumab 40toripalimab 36fludarabine 32Ipilimumab 30Drug Therapy 30Topotecan 29durvalumab 28Vincristine 27Early Intervention, Educational 27Radiotherapy 26Interviews as Topic 26Specimen Handling 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Interventional × capmatinib × Other solid neoplasm × Clear all
NCT01546428 2020-12-19

A Phase I Study of INC280 in Japanese Patients With Advanced Solid Tumors

Novartis

Phase 1 Completed
44 enrolled
Other solid neoplasm

Advanced Solid Tumor

NCT02925104 2020-12-19

A Dose Escalation Study to Assess PK, Safety and Tolerability of INC280 When Taken With Food in cMET Dysregulated Advanced Solid Tumors.

Novartis

Phase 1 Completed
36 enrolled
Other solid neoplasm

cMET Dysegulation Advanced Solid Tumors

NCT02520752 2020-12-10

A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors

Novartis

Phase 1 Completed
37 enrolled
Other solid neoplasm

cMET-dysregulated Advanced Solid Tumors

NCT02626234 2020-12-10

A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors

Novartis

Phase 1 Completed
32 enrolled
Other solid neoplasm

cMET-dysregulated Advanced Solid Tumors

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