Announcements Trials
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Phase

Phase 1 4Phase 2 1

Status

Completed 4Terminated 1

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 6Other solid neoplasm 5Gastrointestinal 4Breast 3Endocrine 2Tumor-Agnostic 1Sarcoma 1Other hematologic neoplasm 1NET 1Lymphoid 1Head & Neck 1Gynecologic 1Dermatologic 1

Conditions

Solid Tumors 2Advanced Solid Tumors 2Histologically or Cytologically Documented Solid Tumors 1

Interventions

Cisplatin 145pembrolizumab 129Carboplatin 125Injections 108Pemetrexed 97Paclitaxel 97Gemcitabine 85Irinotecan 75Nivolumab 71Cyclophosphamide 71Docetaxel 68Bevacizumab 57Oxaliplatin 49Fluorouracil 48atezolizumab 46Capecitabine 46Etoposide 42Leucovorin 41tislelizumab 40toripalimab 36fludarabine 32Ipilimumab 30Drug Therapy 30Topotecan 29durvalumab 28Vincristine 27Early Intervention, Educational 27Radiotherapy 26Interviews as Topic 26Specimen Handling 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × motesanib diphosphate × Other solid neoplasm × Clear all
NCT00861419 2017-02-08

To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.

Amgen

Phase 1 Completed
88 enrolled
Other solid neoplasm

Advanced Solid Tumors

NCT00360867 2015-10-15

An Open Label Treatment Extension Study of AMG 706

Amgen

Phase 2 Terminated
94 enrolled
Other solid neoplasm

Solid Tumors

NCT01386866 2011-07-15

Single Dose Study of [14C]-Labelled AMG 706 in Patients With Advanced Solid Tumors

Amgen

Phase 1 Completed
4 enrolled
Other solid neoplasm

Advanced Solid Tumors

NCT00448786 2011-01-21

Effect of Different Doses of AMG 706 on the Gallbladder in Advanced Solid Tumors

Amgen

Phase 1 Completed
49 enrolled
Other solid neoplasm

Solid Tumors

NCT01235416 2011-01-21

A Phase 1b, Open-label, Dose-finding Study of AMG 706 in Combination With Gemcitabine and Erlotinib to Treat Subjects With Solid Tumors

Amgen

Phase 1 Completed
57 enrolled
Other solid neoplasm

Histologically or Cytologically Documented Solid Tumors

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