Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06888830 2025-06-19

A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Initial Efficacy of JS212 in Subjects With Advanced Malignant Solid Tumour

Phase 1/2 Recruiting

374 enrolled

Other solid neoplasm

Advanced Malignant Solid Tumours

NCT05944237 2025-06-08

HTL0039732 in Participants With Advanced Solid Tumours

Phase 1/2 Recruiting

150 enrolled

EndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Pheochromocytoma, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT06991478 2025-05-28

SK-NK Injection in Patients With Advanced Solid Tumors Accompanied by Malignant Ascites

Phase 1/2 Not yet recruiting

10 enrolled

Other solid neoplasm

Solid Tumor, Malignant Ascites

NCT06970132 2025-05-14

Study of SY-5933 Plus CT-707 in Advanced Solid Tumors With KRAS p.G12C Mutation

Phase 1/2 Not yet recruiting

102 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT02649829 2025-04-29

MESODEC

Phase 1/2 Completed

28 enrolled

GenitourinaryOther solid neoplasmThoracic

Mesothelioma, Malignant, Wilms Tumor

NCT06940349 2025-04-23

COPS-01

Phase 1/2 Recruiting

100 enrolled

Other solid neoplasm

Solid Tumors Refractory to Standard Therapy

NCT03523351 2025-04-20

Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain

Phase 1/2 Completed

78 enrolled 10 charts

Other solid neoplasm

Metastatic Solid Tumors of Metastatic Disease

NCT06895733 2025-03-26

Study of Pazopanib Combined With Palbociclib for Refractory Solid Tumors With Co-amplified in the 11q13(FGF3/4/19/CCND1)

Phase 1/2 Recruiting

65 enrolled

Other solid neoplasm

Solid Tumor, Adult

NCT05146440 2025-03-21

PRIME

Phase 1/2 Recruiting

195 enrolled

Other solid neoplasmSarcoma

Advanced Soft-tissue Sarcoma

NCT06173219 2025-02-27

Safety and Efficacy of Radiotherapy Combined with Immunotherapy for Advanced Malignant Tumors.

Phase 1/2 Recruiting

38 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT03707808 2025-01-20

myDAvIpNi

Phase 1/2 Recruiting

18 enrolled

Other solid neoplasm

Solid Tumor

NCT06139211 2024-12-20

A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors

Phase 1/2 Recruiting

186 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT01291420 2024-12-09

Dendritic Cell Vaccination for Patients with Solid Tumors

Phase 1/2 Completed

48 enrolled

BreastCNSGastrointestinalGenitourinaryOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Renal Cell, Glioblastoma, Sarcoma, Colorectal Neoplasms

NCT06310382 2024-07-08

GH55 for Advanced Cancers With MAPK Mutations: A Study on Safety and Early Results

Phase 1/2 Recruiting

110 enrolled

Other solid neoplasm

Advanced Solid Tumors With MAPK Signal Pathway Mutations

NCT06435455 2024-07-08

GH21 Combined With D-1553 in KRAS G12C Mutant Advanced Solid Tumors

Phase 1/2 Not yet recruiting

126 enrolled

Other solid neoplasm

Locally Advanced or Metastatic Solid Tumors Harboring KRAS G12C Mutation

NCT06081907 2024-05-30

Promise

Phase 1/2 Recruiting

430 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT03319537 2024-05-23

Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma

Phase 1/2 Terminated

9 enrolled 9 charts

Other solid neoplasmThoracic

Mesothelioma

NCT05693844 2024-05-10

Pan-T Booster Co-expressing MSLN CAR T Cell Therapy in Advanced/Metastatic Solid Tumors

Phase 1/2 Recruiting

15 enrolled

Other solid neoplasm

Advanced or Metastatic Solid Tumors

Clinical Trials

Immuno-MESODEC

Metro-PD1

Hyperpolarized 13C MRI as a Biomarker in Advanced Solid Tumors

A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors

COAST

Study of SGN1 in Patients With Advanced Solid Tumor

Study of SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumor

The Effects of Ginseng on Cancer-Related Fatigue

Study of CMTS1215 Injection in Patients With Solid Tumors

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

A Study to Evaluate the Safety, Tolerability, PK, PD, and Preliminary Efficacy of CS01 in Patients With Locally Advanced or Metastatic Solid Tumors

Short Neoadjuvant Hemithoracic IMRT for MPM

A Study to Evaluate Safety, PK and Efficacy of GH55 in Combination With GH21 in Patients With Solid Tumors

A Phase 1/2 Study of CG001419 Tablets in Adult Subjects With Locally Advanced or Metastatic Solid Tumours Harbouring NTRK Gene Abnormalities

Anti-ALPP CAR-T Cells Immunotherapy for Advanced Solid Tumors

ALPP CAR-T Cells for ALPP-Positive Advanced Solid Tumors

SPARTO

Rare Tumor Focused Platform Study of Innovative Therapies and Technologies (PLATFORM2)

Evaluating the Safety, Tolerability, and Preliminary Anti-tumor Activity of MB0151 in Adult Subjects With Advanced Solid Tumors Expressing Somatostatin Receptors

LySATRA

Safety and Tolerability of a mRNA Vaccine Encoding Tumor-Specific Circular RNA Antigens in Combination With Anti-PD-1 Monoclonal Antibody in Patients With Advanced Solid Tumors

Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin

Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma

Chimeric Receptor T Cells With Trastuzumab in HER2+ Advanced Breast Cancer and Other Solid Tumors

A Study of IMM2510 + IMM01 Combination Therapy in Patients With Advanced Solid Tumors

Study on GD2 Positive Solid Tumors by 4SCAR-GD2

Study of Iparomlimab and Tuvonralimab Plus Chemotherapy in Malignant Mesothelioma

NECIM

Phase I/II Study of Ribavirin Given as Monotherapy in Solid Tumour Cancer Patients

A Phase Ib Safety lead-in, Followed by Phase II Trial of ADG106 in Combination With Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer

A Dose Escalation and Dose Expansion Clinical Study of STI-7349 in Subjects With Advanced Solid Tumors

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Initial Efficacy of JS212 in Subjects With Advanced Malignant Solid Tumour

HTL0039732 in Participants With Advanced Solid Tumours

SK-NK Injection in Patients With Advanced Solid Tumors Accompanied by Malignant Ascites

Study of SY-5933 Plus CT-707 in Advanced Solid Tumors With KRAS p.G12C Mutation

MESODEC

COPS-01

Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain

Study of Pazopanib Combined With Palbociclib for Refractory Solid Tumors With Co-amplified in the 11q13(FGF3/4/19/CCND1)

PRIME

Safety and Efficacy of Radiotherapy Combined with Immunotherapy for Advanced Malignant Tumors.

myDAvIpNi

A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors

Dendritic Cell Vaccination for Patients with Solid Tumors

GH55 for Advanced Cancers With MAPK Mutations: A Study on Safety and Early Results

GH21 Combined With D-1553 in KRAS G12C Mutant Advanced Solid Tumors

Promise

Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma

Pan-T Booster Co-expressing MSLN CAR T Cell Therapy in Advanced/Metastatic Solid Tumors