NCT06066424 2026-04-16
Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)
M.D. Anderson Cancer Center
Phase 1 Recruiting
Clinical Trials
480 trialsNCT06576037 2026-04-16
Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT05071846 2026-04-14
MVX-ONCO-2 in Advanced Solid Tumors
University Hospital, Geneva
Phase 1 Active not recruiting
NCT07040943 2026-04-13
Clinical Trial of IL - 22BP Safety, Tolerability, and Antitumor Activity in Refractory Solid Tumors.
West China Hospital
Phase 1 Recruiting
NCT06130254 2026-04-09
Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT07443020 2026-04-07
RIOT 4B
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Phase 1 Recruiting
NCT05521984 2026-04-02
Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)
Washington University School of Medicine
Phase 1 Recruiting
NCT03678350 2026-03-27
Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery
Roswell Park Cancer Institute
Phase 1 Completed
NCT03997370 2026-03-27
Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol
NRG Oncology
Phase 1 Active not recruiting
NCT07490236 2026-03-24
Trilaciclib in Combination With Chemotherapy in Patients With CDK4/6-Dependent Solid Tumors
Hebei Medical University Fourth Hospital
Phase 1 Recruiting
NCT02215720 2026-03-20
TORERO
Gustave Roussy, Cancer Campus, Grand Paris
Phase 1 Completed
NCT03420963 2026-03-20
Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT02789228 2026-03-19
REST
Children's National Research Institute
Phase 1 Active not recruiting
NCT04823897 2026-03-19
A Phase I Open-Label, Single-Arm, Dose-Escalation Clinical and Pharmacology Study of CCI-001 as Monotherapy and in Combination With Standard Chemotherapy in Patients With Recurrent and/or Metastatic Solid Tumours
PharmaMatrix Holdings Ltd
Phase 1 Recruiting
NCT06927297 2026-03-17
Phase I Study of the Safety, Tolerability, and Efficacy of an Engineered Mitochondrial Vaccine in Advanced Solid Tumors
West China Hospital
Phase 1 Recruiting
NCT07469982 2026-03-13
A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors
Shouyao Holdings (Beijing) Co. LTD
Phase 1 Not yet recruiting
NCT04897022 2026-03-12
A Study of Pembrolizumab and Radiation Therapy in People With Mesothelioma
Memorial Sloan Kettering Cancer Center
Phase 1 Active not recruiting
NCT05238792 2026-03-12
Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors
Children's National Research Institute
Phase 1 Recruiting
NCT06563375 2026-03-12
Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT02959463 2026-03-06
Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma
M.D. Anderson Cancer Center
Phase 1 Active not recruiting
NCT05661201 2026-03-06
NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors
Georgetown University
Phase 1 Recruiting
NCT04928508 2026-03-05
Okgyn1
University of Oklahoma
Phase 1 Recruiting
NCT06612645 2026-03-02
CMD03
Chulalongkorn University
Phase 1 Recruiting
NCT07382544 2026-02-25
Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT05100251 2026-02-17
Clinical Trial of WBC100 on Advanced Solid Tumor
Zhejiang University
Phase 1 Terminated
NCT07407985 2026-02-12
GK01IIT-TZ03
Tianjin Medical University Cancer Institute and Hospital
Phase 1 Active not recruiting
NCT04166734 2026-02-04
MESO-PRIME
Royal Marsden NHS Foundation Trust
Phase 1 Terminated
NCT05478486 2026-02-04
Assessment of Safety, Tolerability and PK Profile of MSP008-22 in Patients With Advanced Solid Tumours
Godavari Biorefineries Limited
Phase 1 Completed
NCT07363369 2026-01-23
Exploratory Clinical Study of FAP mRNA Vaccine in Patients With Advanced Malignant Solid Tumors
West China Hospital
Phase 1 Not yet recruiting
NCT07356856 2026-01-21
Efficacy and Safety of Microtransplantation for Advanced and Relapsed Solid Tumors
The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Phase 1 Not yet recruiting
NCT02856425 2026-01-20
PEMBIB
Gustave Roussy, Cancer Campus, Grand Paris
Phase 1 Completed
NCT07351903 2026-01-20
GUARDIAN-02
Tianjin Medical University Cancer Institute and Hospital
Phase 1 Recruiting
NCT07192900 2026-01-15
(RIOT 4A)
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Phase 1 Recruiting
NCT03875287 2026-01-12
Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Active not recruiting
NCT01591356 2026-01-07
EphA2 siRNA in Treating Patients With Advanced or Recurrent Solid Tumors
M.D. Anderson Cancer Center
Phase 1 Active not recruiting
NCT05650749 2025-12-29
GPC2
Children's Hospital of Philadelphia
Phase 1 Recruiting
NCT07100210 2025-12-29
A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity
West China Hospital
Phase 1 Recruiting
NCT01282697 2025-12-22
RAPIRI
University Hospital, Strasbourg, France
Phase 1 Completed
NCT06349837 2025-12-17
Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors
Sichuan University
Phase 1 Recruiting
NCT07285395 2025-12-16
AT1019 Plus SBRT and PD-1 Inhibitor for Advanced Solid Tumors: An IIT Study
The Affiliated Hospital of Xuzhou Medical University
Phase 1 Recruiting
NCT03760575 2025-12-04
Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)
Abramson Cancer Center at Penn Medicine
Phase 1 Recruiting
NCT07260513 2025-12-03
GH2616C102
Suzhou Genhouse Bio Co., Ltd.
Phase 1 Active not recruiting
NCT07257497 2025-12-02
Safety and Efficacy of Combining a Vitamin B6-Limited Diet With Immunotherapy in Solid Tumor Patients: A Clinical Study Protocol
West China Hospital
Phase 1 Not yet recruiting
NCT03618381 2025-11-20
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
Phase 1 Active not recruiting
NCT04483778 2025-11-20
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
Phase 1 Active not recruiting
NCT05038839 2025-11-20
Cabozantinib and Pamiparib for the Treatment of Advanced of Refractory Solid Tumors
M.D. Anderson Cancer Center
Phase 1 Active not recruiting
NCT05608148 2025-11-18
Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors
Kyushu University
Phase 1 Recruiting
NCT06006273 2025-11-10
A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors
M.D. Anderson Cancer Center
Phase 1 Recruiting
NCT07098299 2025-11-06
Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
Barbara Ann Karmanos Cancer Institute
Phase 1 Recruiting
NCT05322408 2025-11-05
HCW9218 in Select Advanced Solid Tumors
Masonic Cancer Center, University of Minnesota
Phase 1 Completed