Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT03420963 2026-03-20

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Phase 1 Terminated

12 enrolled

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT06391918 2026-03-13

Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors

Phase 1 Terminated

37 enrolled

Other solid neoplasm

Solid Tumor, Adult

NCT05381909 2026-02-20

A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors

Phase 1 Terminated

157 enrolled

Other solid neoplasm

Solid Tumor, Adult

NCT05100251 2026-02-17

Clinical Trial of WBC100 on Advanced Solid Tumor

Phase 1 Terminated

68 enrolled

Other solid neoplasm

Solid Tumor

NCT05638334 2026-02-17

Immuno-positron Emission Tomography Study of 89Zr-S095012 in Patients With Advanced Solid Tumours

Phase 1 Terminated

3 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT06331559 2026-02-09

Study of SIM0501 Alone and in Combination in Patients With Advanced Solid Tumors

Phase 1 Terminated

13 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT04166734 2026-02-04

MESO-PRIME

Phase 1 Terminated

5 enrolled 13 charts

Other solid neoplasmThoracic

Mesothelioma

NCT06929260 2026-01-22

A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug Z

Phase 1 Terminated

1 enrolled

Other solid neoplasm

Advanced Solid Tumours

NCT05868915 2026-01-21

HV-101 for Patients With Advanced Solid Tumors

Phase 1 Terminated

1 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT06334783 2026-01-21

TIL for Patients With Advanced Solid Tumor

Phase 1 Terminated

5 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT06299761 2026-01-16

STARMAP

Phase 1 Terminated

19 enrolled

Other solid neoplasm

Solid Tumor

NCT06560632 2026-01-16

POLAR

Phase 1 Terminated

26 enrolled 14 charts

Other solid neoplasm

Advanced Solid Tumor

NCT05012618 2025-12-24

A Dose-escalation Study of LUNA18 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).

Phase 1 Terminated

128 enrolled

Other solid neoplasm

Locally Advanced or Metastatic Solid Tumors

NCT06488716 2025-12-24

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Phase 1 Terminated

12 enrolled

Other solid neoplasm

Solid Tumour

NCT05047536 2025-12-19

KZR-261 in Subjects With Advanced Solid Malignancies

Phase 1 Terminated

61 enrolled 25 charts

DermatologicGastrointestinalOther solid neoplasmThoracic

Uveal Melanoma, Melanoma, Mesothelioma, Neoplasm Metastasis, Colorectal Neoplasms

NCT06509906 2025-12-18

M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)

Phase 1 Terminated

3 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT03968653 2025-12-05

Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid Tumors

Phase 1 Terminated

76 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT05147272 2025-12-05

Study of RP-6306 With Gemcitabine in Advanced Solid Tumors

Phase 1 Terminated

67 enrolled 22 charts

Other solid neoplasm

Adult Solid Tumor

NCT05147350 2025-12-05

MINOTAUR

Phase 1 Terminated

38 enrolled 17 charts

Other solid neoplasm

Advanced Solid Tumor

NCT06232408 2025-11-21

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

Phase 1 Terminated

29 enrolled 15 charts

Other solid neoplasm

Advanced Solid Tumor

NCT06289894 2025-11-21

A Study of BRY805 in Participants With Advanced Solid Tumors

Phase 1 Terminated

13 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT03770494 2025-11-04

A Study of LY3405105 in Participants With Advanced Cancer

Phase 1 Terminated

54 enrolled 26 charts

Other solid neoplasm

Solid Tumor

NCT02597036 2025-10-23

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

Phase 1 Terminated

62 enrolled 25 charts

Other solid neoplasm

Solid Tumors

NCT05859464 2025-10-20

A Phase 1 Study of ZL-1218 in Subjects With Advanced Solid Tumors

Phase 1 Terminated

34 enrolled

Other solid neoplasm

Malignant Solid Tumor

NCT04272034 2025-10-16

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Phase 1 Terminated

105 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Nasopharyngeal Carcinoma, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Mesothelioma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT06336148 2025-10-15

A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors

Phase 1 Terminated

10 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Melanoma, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT03522142 2025-10-09

A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

Phase 1 Terminated

83 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT05976334 2025-10-06

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Phase 1 Terminated

3 enrolled 19 charts

Other solid neoplasm

Solid Tumors

NCT06182579 2025-09-17

Phase I Study of RiMO-401 With Radiation in Advanced Tumors

Phase 1 Terminated

5 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT04242147 2025-09-16

A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KD033 (SAR445710) in Subjects With Metastatic or Locally Advanced Solid Tumors

Phase 1 Terminated

45 enrolled

Other solid neoplasm

Solid Tumor

NCT04249843 2025-09-11

Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors

Phase 1 Terminated

109 enrolled

Other solid neoplasm

Solid Tumor

NCT05707676 2025-09-11

MEETCD8-001

Phase 1 Terminated

40 enrolled

Other solid neoplasm

Solid Tumor

NCT06074705 2025-08-22

A Study of DS-1471a In Subjects With Advanced Solid Tumors

Phase 1 Terminated

17 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT05109650 2025-08-12

Assessment of Safety and Preliminary Efficacy With BAT6026 in Solid Tumour Patients

Phase 1 Terminated

13 enrolled

Other solid neoplasm

Advanced Solid Tumour

NCT03034304 2025-07-24

A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors

Phase 1 Terminated

105 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT06299163 2025-07-23

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

Phase 1 Terminated

11 enrolled

BreastDermatologicGenitourinaryGynecologicOther solid neoplasmSarcomaThoracic

Adenocarcinoma of Lung, Mesothelioma, Malignant, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Leiomyosarcoma, Liposarcoma, Melanoma, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

Clinical Trials

A Study to Find a Suitable Dose of BI 1821736 and Test Whether it Helps People With Advanced Cancer

Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid Tumors

EPRAD

An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors

A Study of BGB-R046 as Monotherapy and in Combination With Tislelizumab in Solid Tumors

A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors

Combination of Serabelisib and Insulin Suppressing Diet With or Without Nab-paclitaxel in Subjects With Advanced Solid Tumors With PIK3CA Mutations

GT201

A Study of NB004 as Monotherapy or Combination Therapy in Patients With Advanced Solid Tumors

SUMMIT-1

A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function

To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors

Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors

A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors

Clinical Trial of WBC100 on Advanced Solid Tumor

Immuno-positron Emission Tomography Study of 89Zr-S095012 in Patients With Advanced Solid Tumours

Study of SIM0501 Alone and in Combination in Patients With Advanced Solid Tumors

MESO-PRIME

A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug Z

HV-101 for Patients With Advanced Solid Tumors

TIL for Patients With Advanced Solid Tumor

STARMAP

POLAR

A Dose-escalation Study of LUNA18 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

KZR-261 in Subjects With Advanced Solid Malignancies

M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)

Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid Tumors

Study of RP-6306 With Gemcitabine in Advanced Solid Tumors

MINOTAUR

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

A Study of BRY805 in Participants With Advanced Solid Tumors

A Study of LY3405105 in Participants With Advanced Cancer

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

A Phase 1 Study of ZL-1218 in Subjects With Advanced Solid Tumors

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors

A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Phase I Study of RiMO-401 With Radiation in Advanced Tumors

A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KD033 (SAR445710) in Subjects With Metastatic or Locally Advanced Solid Tumors

Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors

MEETCD8-001

A Study of DS-1471a In Subjects With Advanced Solid Tumors

Assessment of Safety and Preliminary Efficacy With BAT6026 in Solid Tumour Patients

A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors