Announcements Trials
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Phase

Phase 2 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Observational 1Interventional 1

Sponsor

Cancer Type

Gastrointestinal 441Thoracic 50Gynecologic 37Breast 32Genitourinary 29Head & Neck 26Sarcoma 14Endocrine 9Dermatologic 9Other solid neoplasm 6NET 6CNS 5Plasma cell 2Other hematologic neoplasm 2Lymphoid 2Other neoplasm 1Myeloid 1

Conditions

Multiple Myeloma 3577Neoplasms, Plasma Cell 696Lymphoma 531Lymphoma, Non-Hodgkin 480Leukemia, Lymphocytic, Chronic, B-Cell 409Hodgkin Disease 405Recurrence 404Precursor Cell Lymphoblastic Leukemia-Lymphoma 375Leukemia 373Leukemia, Myeloid, Acute 363Myelodysplastic Syndromes 331Lymphoma, Large B-Cell, Diffuse 290Lymphoma, Mantle-Cell 288Lymphoma, Follicular 284Lymphoma, B-Cell, Marginal Zone 256Burkitt Lymphoma 249Immunoglobulin Light-chain Amyloidosis 227Myeloproliferative Disorders 226Lymphoma, Large-Cell, Immunoblastic 223Neoplasms 214Hematologic Neoplasms 200Primary Myelofibrosis 186Leukemia, Myeloid, Chronic-Phase 182Leukemia, Myeloid, Accelerated Phase 173Lymphoma, T-Cell, Cutaneous 170Waldenstrom Macroglobulinemia 164Blast Crisis 162Leukemia, Myelomonocytic, Chronic 158Mycosis Fungoides 147Sezary Syndrome 146

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Biliary Tract Neoplasms × Plasma cell × Clear all
NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

Novartis

Phase 2 Completed
206 enrolled 40 charts 2 FDA
CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

NCT02900248 2019-04-02

N1

CureOne

Terminated
23 enrolled
BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellSarcomaThoracic

Anus Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

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