Announcements Trials
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Phase

Phase 2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gastrointestinal 58Gynecologic 7Genitourinary 7Thoracic 6Breast 4Sarcoma 2Head & Neck 2Endocrine 2Dermatologic 2CNS 2Plasma cell 1Other solid neoplasm 1Other hematologic neoplasm 1

Conditions

Multiple Myeloma 873Neoplasms, Plasma Cell 162Lymphoma, Non-Hodgkin 139Lymphoma 135Hodgkin Disease 134Leukemia, Lymphocytic, Chronic, B-Cell 118Precursor Cell Lymphoblastic Leukemia-Lymphoma 109Myelodysplastic Syndromes 103Recurrence 101Leukemia, Myeloid, Acute 99Leukemia 94Lymphoma, Mantle-Cell 80Lymphoma, Large B-Cell, Diffuse 76Lymphoma, Follicular 73Myeloproliferative Disorders 69Lymphoma, B-Cell, Marginal Zone 69Hematologic Neoplasms 64Burkitt Lymphoma 64Primary Myelofibrosis 57Lymphoma, Large-Cell, Immunoblastic 55Waldenstrom Macroglobulinemia 52Leukemia, Myelogenous, Chronic, BCR-ABL Positive 52Leukemia, Myeloid, Chronic-Phase 46Lymphoma, T-Cell, Cutaneous 44Immunoglobulin Light-chain Amyloidosis 43Congenital Abnormalities 43Neoplasms 41Leukemia, Myelomonocytic, Chronic 41Leukemia, Myeloid, Accelerated Phase 40Sezary Syndrome 38

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Biliary Tract Neoplasms × Plasma cell × Clear all
NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

Novartis

Phase 2 Completed
206 enrolled 40 charts 2 FDA
CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

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