Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase NA 1Phase 4 1

Status

Recruiting 2Not yet recruiting 1Enrolling by invitation 1Completed 1

Sponsor Class

OTHER 3NIH 1INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Plasma cell 5Lymphoid 4Other hematologic neoplasm 3

Conditions

Multiple Myeloma 449Lymphoma 55Recurrence 45Neoplasms, Plasma Cell 35Immunoglobulin Light-chain Amyloidosis 34Hematologic Neoplasms 34Smoldering Multiple Myeloma 28Lymphoma, Non-Hodgkin 27Leukemia, Myeloid, Acute 22Leukemia, Lymphocytic, Chronic, B-Cell 21Neoplasms 20Precursor Cell Lymphoblastic Leukemia-Lymphoma 19Hodgkin Disease 18Myelodysplastic Syndromes 17Monoclonal Gammopathy of Undetermined Significance 13Leukemia 12Waldenstrom Macroglobulinemia 11Lymphoma, Mantle-Cell 11Leukemia, Myelogenous, Chronic, BCR-ABL Positive 11Breast Neoplasms 11Prostatic Neoplasms 10Lymphoma, Large B-Cell, Diffuse 10Paraproteinemias 9Ovarian Neoplasms 9Amyloidosis 9Lung Neoplasms 8Leukemia, Plasma Cell 8Primary Myelofibrosis 7Melanoma 7Lymphoma, Follicular 7

Interventions

tocilizumab 2talquetamab 1siltuximab 1Dexamethasone 1Calcium Dobesilate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Cytokine Release Syndrome × Plasma cell × 90 days × Clear all
NCT04975555 2026-06-03

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

University of Alabama at Birmingham

Phase 2 Completed
24 enrolled 8 charts
LymphoidOther hematologic neoplasmPlasma cell

Cytokine Release Syndrome, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07499128 2026-06-01

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event

National Institutes of Health Clinical Center (CC)

Phase NA Enrolling by invitation
136 enrolled
LymphoidOther hematologic neoplasmPlasma cell

Cytokine Release Syndrome, Lymphoma, Multiple Myeloma, Neoplasms, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07609940 2026-05-27

POPLIN

Regeneron Pharmaceuticals

Phase 4 Not yet recruiting
30 enrolled
Plasma cell

Cytokine Release Syndrome, Multiple Myeloma

NCT06421675 2026-04-27

EMBRACE

Ontario Clinical Oncology Group (OCOG)

Phase 2 Recruiting
40 enrolled
Plasma cell

Cytokine Release Syndrome, Multiple Myeloma, Recurrence

NCT05972135 2026-04-22

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

SCRI Development Innovations, LLC

Phase 2 Recruiting
100 enrolled
Plasma cell

Cytokine Release Syndrome, Multiple Myeloma

Data powered by HemOnc (CC BY 4.0) Colophon âš¡