Announcements Trials
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Phase

Phase 2 1

Status

Recruiting 4Withdrawn 1Unknown 1Not yet recruiting 1Enrolling by invitation 1Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 5Plasma cell 1Other hematologic neoplasm 1CNS 1

Conditions

Multiple Myeloma 1663Neoplasms, Plasma Cell 415Lymphoma, Non-Hodgkin 311Lymphoma 283Hodgkin Disease 281Leukemia, Lymphocytic, Chronic, B-Cell 274Precursor Cell Lymphoblastic Leukemia-Lymphoma 246Leukemia, Myeloid, Acute 223Leukemia 220Lymphoma, Mantle-Cell 196Lymphoma, Large B-Cell, Diffuse 196Lymphoma, Follicular 196Myelodysplastic Syndromes 194Recurrence 185Lymphoma, B-Cell, Marginal Zone 178Burkitt Lymphoma 172Lymphoma, Large-Cell, Immunoblastic 161Myeloproliferative Disorders 146Leukemia, Myeloid, Chronic-Phase 134Leukemia, Myeloid, Accelerated Phase 122Primary Myelofibrosis 121Immunoglobulin Light-chain Amyloidosis 120Waldenstrom Macroglobulinemia 119Lymphoma, T-Cell, Cutaneous 119Blast Crisis 114Leukemia, Myelomonocytic, Chronic 105Sezary Syndrome 100Mycosis Fungoides 100Neoplasms 97Leukemia, Hairy Cell 95

Interventions

siltuximab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Cytokine Release Syndrome × Plasma cell × Clear all
NCT04975555 2026-06-03

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

University of Alabama at Birmingham

Phase 2 Completed
24 enrolled 8 charts
LymphoidOther hematologic neoplasmPlasma cell

Cytokine Release Syndrome, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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