Announcements Trials
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Phase

Phase 1 2Phase 3 1Phase 2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 108Gastrointestinal 108CNS 8Gynecologic 6Endocrine 5Head & Neck 3Genitourinary 3Other hematologic neoplasm 2Dermatologic 2Thoracic 1Plasma cell 1Other 1NET 1Classical hematology 1Breast 1

Conditions

Multiple Myeloma 1086Neoplasms, Plasma Cell 255Lymphoma 157Lymphoma, Non-Hodgkin 150Hodgkin Disease 135Recurrence 130Leukemia, Lymphocytic, Chronic, B-Cell 130Precursor Cell Lymphoblastic Leukemia-Lymphoma 116Myelodysplastic Syndromes 111Leukemia 109Leukemia, Myeloid, Acute 106Lymphoma, Follicular 84Lymphoma, Mantle-Cell 83Lymphoma, B-Cell, Marginal Zone 82Burkitt Lymphoma 76Lymphoma, Large B-Cell, Diffuse 74Myeloproliferative Disorders 70Immunoglobulin Light-chain Amyloidosis 67Lymphoma, Large-Cell, Immunoblastic 65Hematologic Neoplasms 63Primary Myelofibrosis 58Leukemia, Myeloid, Chronic-Phase 57Leukemia, Myeloid, Accelerated Phase 51Leukemia, Myelogenous, Chronic, BCR-ABL Positive 49Waldenstrom Macroglobulinemia 46Blast Crisis 44Congenital Abnormalities 43Leukemia, Myelomonocytic, Chronic 42Dendritic Cell Sarcoma, Interdigitating 42Smoldering Multiple Myeloma 41

Interventions

trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2 × Gastrointestinal Stromal Tumors × Plasma cell × Clear all
NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

Novartis

Phase 2 Completed
206 enrolled 40 charts 2 FDA
CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

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