Announcements Trials
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Phase

Phase 3 1Phase 1 1

Status

Completed 2Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1NETWORK 1

Study Type

Observational 2Interventional 2

Sponsor

Cancer Type

Plasma cell 4

Conditions

Multiple Myeloma 47Lymphoma 18Myelodysplastic Syndromes 4Immunoglobulin Light-chain Amyloidosis 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Ovarian Neoplasms 2Neoplasms, Plasma Cell 2Lymphoma, Non-Hodgkin 2Lymphoma, Large-Cell, Anaplastic 2Leukemia, Myeloid, Acute 2Leukemia, Lymphocytic, Chronic, B-Cell 2Hematologic Neoplasms 2Breast Neoplasms 2Amyloidosis, Hereditary, Transthyretin-Related 2Amyloidosis 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Trigger Finger Disorder 1Thyroid Neoplasms 1Thrombocythemia, Essential 1Testicular Germ Cell Tumor 1Stomach Neoplasms 1Spinal Stenosis 1Smoldering Multiple Myeloma 1Rectal Neoplasms 1Prostatic Neoplasms 1Primary Myelofibrosis 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1

Interventions

Dexamethasone 50Melphalan 29Cyclophosphamide 25Bortezomib 24Filgrastim 18Calcium Dobesilate 18Peripheral Blood Stem Cell Transplantation 16daratumumab 13pomalidomide 10dexamethasone acetate 8Lenalidomide 8fludarabine phosphate 7ixazomib 6dexamethasone 21-phosphate 6Whole-Body Irradiation 6Mycophenolic Acid 6venetoclax 5birtamimab 5auricularum 5Thalidomide 5Granulocyte Colony-Stimulating Factor 5Cyclosporine 5Busulfan 5Radiotherapy 4Interferon-alpha 4Etoposide 4Carboplatin 4Biopsy 4sargramostim 3miridesap 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Immunoglobulin Light-chain Amyloidosis × Biopsy × Plasma cell × Clear all
NCT04847453 2026-05-13

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

National Cancer Institute (NCI)

Phase 1 Active not recruiting
24 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT06022939 2026-05-06

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

SWOG Cancer Research Network

Phase 3 Recruiting
338 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis

NCT03886155 2021-12-22

CAST

The Cleveland Clinic

Completed
107 enrolled
Plasma cell

Amyloidosis, Hereditary, Transthyretin-Related, Immunoglobulin Light-chain Amyloidosis, Amyloidosis, Trigger Finger Disorder

NCT03923920 2021-12-22

ALF

The Cleveland Clinic

Completed
200 enrolled
Plasma cell

Amyloidosis, Hereditary, Transthyretin-Related, Immunoglobulin Light-chain Amyloidosis, Alzheimer Disease, Amyloidosis, Spinal Stenosis

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