Clinical Trials

35 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT07079423 2025-07-23

Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis

35 enrolled

Phase 2 Not yet recruiting

Immunoglobulin Light-chain Amyloidosis

NCT07055724 2025-07-09

Study of Eque-cel CAR-T Therapy in Newly Diagnosed Severe AL Amyloidosis

17 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT06935162 2025-05-25

Teclistamab in Previously Treated AL Amyloidosis

30 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT06971380 2025-05-14

Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain Amyloidosis

180 enrolled

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma, Recurrence

NCT04304144 2025-03-05

A Study to Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL Amyloidosis

25 enrolled 14 charts

Immunoglobulin Light-chain Amyloidosis

NCT04895917 2025-02-20

DarPAL

27 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT06342466 2024-12-30

Bortezomib, Pomalidomide, Dexamethasone for Systemic AL Amyloidosis

40 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT05968846 2024-12-05

Repeat PET/CT Imaging of Patients With Amyloid 124I-AT-01 to Measure Changes in Organ-specific Amyloid Load

19 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT06418477 2024-10-01

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients with MIDD

20 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT05066607 2024-03-06

IsAMYP

Phase 2 Unknown

46 enrolled

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT00520767 2023-12-22

Bortezomib, Melphalan, and Dexamethasone in Treating Patients With Primary Amyloidosis or Light Chain Deposition Disease

35 enrolled 7 charts

Immunoglobulin Light-chain Amyloidosis

NCT05028374 2023-12-20

COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies

LymphoidOther hematologic neoplasmPlasma cell

119 enrolled 11 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00003353 2023-06-22

High-Dose Melphalan Plus Peripheral Stem Cell Transplantation in Treating Patients With Primary Systemic Amyloidosis

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma, Neoplasms, Plasma Cell

NCT00224393 2023-05-30

Phase II Trial of Enbrel in Patients With Primary Systemic Amyloidosis

60 enrolled

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT02994784 2023-05-24

Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis Patients

27 enrolled 13 charts

Immunoglobulin Light-chain Amyloidosis

NCT03252600 2023-01-25

Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary Amyloidosis

Phase 2 Unknown

53 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT01849783 2022-05-11

Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma

41 enrolled 12 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT04474938 2022-05-10

Daratumumab Combined With Bortezomib and Dexamethasone in Mayo 04 Stage III Light Chain Amyloidosis

Phase 2 Unknown

40 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT02207556 2021-07-09

DUAL

32 enrolled 15 charts

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT01083316 2020-09-25

Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis

35 enrolled 9 charts

Immunoglobulin Light-chain Amyloidosis, Alzheimer Disease, Amyloidosis

NCT00075621 2020-09-17

Tandem Autologous Stem Cell Transplantation in Treating Patients With Primary Systemic (AL) Amyloidosis

62 enrolled

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT01222260 2020-03-30

Bendamustine and Dexamethasone in Patients With Relapsed AL Amyloidosis

40 enrolled 10 charts

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT00651937 2020-01-14

Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden

80 enrolled 7 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT02613182 2019-05-16

OLE

34 enrolled 10 charts

Immunoglobulin Light-chain Amyloidosis

NCT02632786 2019-04-05

PRONTO

129 enrolled 18 charts

Immunoglobulin Light-chain Amyloidosis, Alzheimer Disease, Amyloidosis, Paraproteinemias

NCT03154047 2019-03-26

Study in Subjects With Light Chain (AL) Amyloidosis

80 enrolled 9 charts

Immunoglobulin Light-chain Amyloidosis

NCT00064337 2018-08-09

S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic Amyloidosis

104 enrolled 6 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT01511263 2018-03-21

EpiCardiAL

86 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT01531751 2018-03-21

DIACAL

Phase 2 Withdrawn

Immunoglobulin Light-chain Amyloidosis

NCT01510613 2018-03-12

Pomalidomide and Dexamethasone (PDex) in AL Amyloidosis

28 enrolled

Immunoglobulin Light-chain Amyloidosis

NCT01677286 2017-08-01

Safety and Effect of Doxycycline in Patients With Amyloidosis

25 enrolled 13 charts

AA amyloidosis, Immunoglobulin Light-chain Amyloidosis, Amyloidosis, Amyloidosis, Familial

NCT00681044 2017-04-28

HD Melphalan and SCT in Patients With IGDD or LCDD

5 enrolled 7 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT01194791 2017-04-25

LENDEXAL

30 enrolled

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT00091260 2017-02-20

CC-5013 With or Without Dexamethasone in Treating Patients With Primary Systemic Amyloidosis

82 enrolled 9 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT00679367 2017-02-20

MRD

16 enrolled 9 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT00416624 2017-02-10

Epoetin Alfa or Darbepoetin Alfa in Treating Patients With Anemia Caused by Chemotherapy

Classical hematologyDermatologicLymphoidOther hematologic neoplasmOther neoplasmPlasma cell

239 enrolled 23 charts

Immunoglobulin Light-chain Amyloidosis, Anemia, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Mycosis Fungoides, Precancerous Conditions, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell

NCT00790647 2017-02-06

Melphalan, Bortezomib, and Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis

10 enrolled 9 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma

NCT00075608 2017-01-27

2nd Autologous Stem Cell Transplant in Patients With Persistent/Recurrent (AL) Amyloidosis

12 enrolled 6 charts