Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 39Dermatologic 4Thoracic 3Gastrointestinal 3Plasma cell 2Gynecologic 2Genitourinary 2Lymphoid 1Head & Neck 1Breast 1

Conditions

Multiple Myeloma 3577Neoplasms, Plasma Cell 696Lymphoma 531Lymphoma, Non-Hodgkin 480Leukemia, Lymphocytic, Chronic, B-Cell 409Hodgkin Disease 405Recurrence 404Precursor Cell Lymphoblastic Leukemia-Lymphoma 375Leukemia 373Leukemia, Myeloid, Acute 363Myelodysplastic Syndromes 331Lymphoma, Large B-Cell, Diffuse 290Lymphoma, Mantle-Cell 288Lymphoma, Follicular 284Lymphoma, B-Cell, Marginal Zone 256Burkitt Lymphoma 249Immunoglobulin Light-chain Amyloidosis 227Myeloproliferative Disorders 226Lymphoma, Large-Cell, Immunoblastic 223Neoplasms 214Hematologic Neoplasms 200Primary Myelofibrosis 186Leukemia, Myeloid, Chronic-Phase 182Leukemia, Myeloid, Accelerated Phase 173Lymphoma, T-Cell, Cutaneous 170Waldenstrom Macroglobulinemia 164Blast Crisis 162Leukemia, Myelomonocytic, Chronic 158Mycosis Fungoides 147Sezary Syndrome 146

Interventions

selinexor 1pazopanib 1fludarabine 1Proton Therapy 1Ifosfamide 1Doxorubicin 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Liposarcoma, Myxoid × Plasma cell × Clear all
NCT06239272 2026-05-19

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

St. Jude Children's Research Hospital

Phase 1/2 Recruiting
139 enrolled
Plasma cellSarcoma

Histiocytoma, Angiomatoid Fibrous, Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Glomus Tumor, Granuloma, Plasma Cell, Hemangiosarcoma, Liposarcoma, Myoepithelioma, Sarcoma, Osteosarcoma, Disorders of Sex Development, Granular Cell Tumor, Neoplasms, Adipose Tissue, Liposarcoma, Myxoid, Dermatofibrosarcoma, Sarcoma, Clear Cell, Smooth Muscle Tumor, Nerve Sheath Neoplasms, Neurofibrosarcoma, Hemangioendothelioma, Epithelioid, Vascular Neoplasms, Solitary Fibrous Tumors

NCT03399448 2023-06-22

NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)

University of Pennsylvania

Phase 1 Terminated
3 enrolled
DermatologicPlasma cellSarcoma

Melanoma, Multiple Myeloma, Sarcoma, Synovial, Liposarcoma, Myxoid

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