Announcements Trials
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Phase

Phase 1 2

Status

Unknown 1Terminated 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 16Dermatologic 7Gynecologic 6Thoracic 4Gastrointestinal 4Breast 3Plasma cell 2Head & Neck 2Genitourinary 2CNS 2

Conditions

Multiple Myeloma 336Neoplasms, Plasma Cell 99Myelodysplastic Syndromes 89Leukemia, Lymphocytic, Chronic, B-Cell 89Precursor Cell Lymphoblastic Leukemia-Lymphoma 88Hodgkin Disease 85Lymphoma, Non-Hodgkin 84Leukemia, Myeloid, Acute 83Lymphoma, Follicular 71Leukemia 71Lymphoma 69Lymphoma, Mantle-Cell 67Lymphoma, B-Cell, Marginal Zone 63Burkitt Lymphoma 63Lymphoma, Large B-Cell, Diffuse 59Lymphoma, Large-Cell, Immunoblastic 55Recurrence 52Myeloproliferative Disorders 49Leukemia, Myeloid, Chronic-Phase 48Primary Myelofibrosis 46Leukemia, Myeloid, Accelerated Phase 43Leukemia, Myelomonocytic, Chronic 41Leukemia, Myelogenous, Chronic, BCR-ABL Positive 38Dendritic Cell Sarcoma, Interdigitating 37Congenital Abnormalities 35Blast Crisis 34Waldenstrom Macroglobulinemia 27Myelodysplastic-Myeloproliferative Diseases 25Lymphoma, T-Cell, Cutaneous 25Immunoglobulin Light-chain Amyloidosis 25

Interventions

fludarabine 2Cyclophosphamide 2pazopanib 1Radiotherapy 1Radiation 1Quality of Life 1Patient Reported Outcome Measures 1Molecular Diagnostic Techniques 1Immunotherapy, Adoptive 1Immunotherapy 1Imatinib Mesylate 1Ifosfamide 1Drug Therapy 1Doxorubicin 1Biological Therapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Sarcoma, Synovial × Cyclophosphamide × Plasma cell × Clear all
NCT03399448 2023-06-22

NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)

University of Pennsylvania

Phase 1 Terminated
3 enrolled
DermatologicPlasma cellSarcoma

Melanoma, Multiple Myeloma, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT02457650 2016-08-03

T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies

Shenzhen Second People's Hospital

Phase 1 Unknown
36 enrolled
BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicPlasma cellSarcomaThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Synovial

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