Announcements Trials
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Phase

Phase 1 2

Status

Unknown 1Terminated 1

Sponsor Class

INDUSTRY 3OTHER 2NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 58CNS 8Gynecologic 7Gastrointestinal 7Dermatologic 7Thoracic 4Genitourinary 4Plasma cell 2Other solid neoplasm 2Breast 2NET 1Lymphoid 1Head & Neck 1Endocrine 1

Conditions

Multiple Myeloma 2123Neoplasms, Plasma Cell 505Lymphoma 355Lymphoma, Non-Hodgkin 334Hodgkin Disease 329Leukemia, Lymphocytic, Chronic, B-Cell 307Precursor Cell Lymphoblastic Leukemia-Lymphoma 299Leukemia 290Leukemia, Myeloid, Acute 270Myelodysplastic Syndromes 263Lymphoma, Mantle-Cell 228Lymphoma, Follicular 224Lymphoma, Large B-Cell, Diffuse 216Lymphoma, B-Cell, Marginal Zone 206Burkitt Lymphoma 201Recurrence 188Myeloproliferative Disorders 182Lymphoma, Large-Cell, Immunoblastic 182Immunoglobulin Light-chain Amyloidosis 163Primary Myelofibrosis 153Leukemia, Myeloid, Chronic-Phase 152Leukemia, Myeloid, Accelerated Phase 143Lymphoma, T-Cell, Cutaneous 140Leukemia, Myelomonocytic, Chronic 133Blast Crisis 131Mycosis Fungoides 126Sezary Syndrome 125Congenital Abnormalities 122Waldenstrom Macroglobulinemia 121Leukemia, Hairy Cell 110

Interventions

fludarabine 2Cyclophosphamide 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Sarcoma, Synovial × Plasma cell × Clear all
NCT03399448 2023-06-22

NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)

University of Pennsylvania

Phase 1 Terminated
3 enrolled
DermatologicPlasma cellSarcoma

Melanoma, Multiple Myeloma, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT02457650 2016-08-03

T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies

Shenzhen Second People's Hospital

Phase 1 Unknown
36 enrolled
BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicPlasma cellSarcomaThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Synovial

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