Announcements Trials
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Phase

Phase 2/3 2

Status

Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 24Endocrine 24Thoracic 6Gynecologic 6Gastrointestinal 3CNS 3Plasma cell 2Other hematologic neoplasm 2NET 2Myeloid 2Dermatologic 2Sarcoma 1Lymphoid 1Genitourinary 1Breast 1

Conditions

Multiple Myeloma 937Lymphoma 113Recurrence 93Neoplasms, Plasma Cell 92Lymphoma, Non-Hodgkin 68Immunoglobulin Light-chain Amyloidosis 60Hematologic Neoplasms 60Neoplasms 54Smoldering Multiple Myeloma 52Leukemia, Myeloid, Acute 51Leukemia 51Myelodysplastic Syndromes 47Leukemia, Lymphocytic, Chronic, B-Cell 45Precursor Cell Lymphoblastic Leukemia-Lymphoma 38Hodgkin Disease 38Leukemia, Plasma Cell 27Myeloproliferative Disorders 24Breast Neoplasms 24Monoclonal Gammopathy of Undetermined Significance 23Lymphoma, Large B-Cell, Diffuse 23Lymphoma, Mantle-Cell 22Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22Amyloidosis 22Primary Myelofibrosis 21Lymphoma, Follicular 21Waldenstrom Macroglobulinemia 20Ovarian Neoplasms 20Lymphoma, B-Cell, Marginal Zone 17Lymphoma, B-Cell 17Colorectal Neoplasms 17

Interventions

trametinib 1dabrafenib 1cobimetinib 1Vemurafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Thyroid Carcinoma, Anaplastic × Plasma cell × 1 year × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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