Announcements Trials
Browse Landscape

Phase

Phase 1 2Phase 2 1

Status

Completed 2Active not recruiting 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Breast 49Gastrointestinal 43Genitourinary 41Gynecologic 27Other 24Head & Neck 21Thoracic 20CNS 15Other hematologic neoplasm 11Lymphoid 11Dermatologic 8Tumor-Agnostic 7Sarcoma 6Other solid neoplasm 5Plasma cell 3Endocrine 3NET 2Classical hematology 2Other neoplasm 1

Conditions

Multiple Myeloma 2Weight Loss 1Thrombocytopenia 1Splenomegaly 1Smoldering Multiple Myeloma 1Monoclonal Gammopathy of Undetermined Significance 1Lymphocytosis 1Lymphadenopathy 1Leukemia, Lymphocytic, Chronic, B-Cell 1Fever 1Fatigue 1Anemia 1

Interventions

Dexamethasone 870Lenalidomide 456Bortezomib 454Cyclophosphamide 365Melphalan 271Calcium Dobesilate 262daratumumab 233pomalidomide 207carfilzomib 182fludarabine phosphate 140fludarabine 136Thalidomide 125Peripheral Blood Stem Cell Transplantation 119Filgrastim 114ixazomib 93Mycophenolic Acid 90Granulocyte Colony-Stimulating Factor 89Whole-Body Irradiation 87Busulfan 87dexamethasone acetate 86Tacrolimus 78dexamethasone 21-phosphate 74Cyclosporine 68isatuximab 67auricularum 67Prednisone 65elotuzumab 58belantamab mafodotin 56Antilymphocyte Serum 56Etoposide 53

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Metformin × Plasma cell × Clear all
NCT04850846 2026-02-09

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

Dana-Farber Cancer Institute

Phase 2 Active not recruiting
60 enrolled 10 charts
Plasma cell

Smoldering Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance

NCT03829020 2024-08-22

Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma

Mayo Clinic

Phase 1 Completed
9 enrolled
Plasma cell

Multiple Myeloma

NCT02948283 2021-02-12

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

City of Hope Medical Center

Phase 1 Completed
3 enrolled
Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

Lymphadenopathy, Anemia, Fatigue, Fever, Lymphocytosis, Multiple Myeloma, Splenomegaly, Thrombocytopenia, Weight Loss, Leukemia, Lymphocytic, Chronic, B-Cell

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