Announcements Trials
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Phase

Phase 1 3Phase 2 1Phase 1/2 1

Status

Completed 3Terminated 1Suspended 1

Sponsor Class

OTHER 28NIH 5NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Sarcoma 15Other hematologic neoplasm 14Lymphoid 13Gynecologic 10Genitourinary 7Dermatologic 7CNS 7Plasma cell 5Other solid neoplasm 4Gastrointestinal 4Thoracic 3Head & Neck 2Breast 2Tumor-Agnostic 1Myeloid 1Classical hematology 1

Conditions

Multiple Myeloma 5Lymphoma, Non-Hodgkin 1Lymphoma 1Leukemia 1Hodgkin Disease 1

Interventions

Dexamethasone 36Melphalan 29Cyclophosphamide 28Specimen Handling 26Biopsy 26Bortezomib 24Calcium Dobesilate 20Magnetic Resonance Spectroscopy 19Lenalidomide 17fludarabine phosphate 15Filgrastim 15Peripheral Blood Stem Cell Transplantation 13Vincristine 12Prednisone 12dexamethasone acetate 11dexamethasone 21-phosphate 11auricularum 11carfilzomib 10Doxorubicin 10sargramostim 9fludarabine 8Thalidomide 8Interferon-alpha 7Cyclosporine 7Busulfan 7trametinib 6ixazomib 6Rituximab 6Etoposide 6daratumumab 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
NIH × Sirolimus × Plasma cell × Clear all
NCT06876142 2026-06-05

Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma

National Institutes of Health Clinical Center (CC)

Phase 1/2 Suspended
54 enrolled
Plasma cell

Multiple Myeloma

NCT00973804 2019-12-17

Pilot Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Matched Unrelated Double Cord Blood Transplant for the Treatment of Leukemias, Lymphomas, and Pre-Malignant Blood Disorders

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
4 enrolled
LymphoidOther hematologic neoplasmPlasma cell

Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma

NCT00693433 2015-12-04

Temsirolimus and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma

National Cancer Institute (NCI)

Phase 1 Completed
15 enrolled
Plasma cell

Multiple Myeloma

NCT00079456 2013-10-11

Temsirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma

National Cancer Institute (NCI)

Phase 2 Completed
25 enrolled
Plasma cell

Multiple Myeloma

NCT00398515 2013-09-30

Lenalidomide and Temsirolimus in Treating Patients With Previously Treated Multiple Myeloma

National Cancer Institute (NCI)

Phase 1 Completed
25 enrolled
Plasma cell

Multiple Myeloma

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