Announcements Trials
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Phase

Phase 2 2Phase 1 1

Status

Active not recruiting 6Completed 3Recruiting 2Withdrawn 1Terminated 1Not yet recruiting 1

Sponsor Class

INDUSTRY 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Dermatologic 37Gastrointestinal 19Thoracic 11Tumor-Agnostic 9Other hematologic neoplasm 6Head & Neck 5CNS 5Breast 5Sarcoma 3Plasma cell 3Other solid neoplasm 3Endocrine 3Myeloid 2Gynecologic 2Lymphoid 1

Conditions

Multiple Myeloma 3Neoplasms 2Thyroid Carcinoma, Anaplastic 1Nonseminomatous germ cell tumor 1Leukemia, Hairy Cell 1Glioma 1Gastrointestinal Stromal Tumors 1Biliary Tract Neoplasms 1

Interventions

Dexamethasone 393Bortezomib 246Lenalidomide 222Cyclophosphamide 184Melphalan 168Calcium Dobesilate 119Peripheral Blood Stem Cell Transplantation 94fludarabine phosphate 89Thalidomide 82Filgrastim 74carfilzomib 70pomalidomide 68Granulocyte Colony-Stimulating Factor 63Busulfan 63Mycophenolic Acid 61daratumumab 58Whole-Body Irradiation 57ixazomib 54fludarabine 52Tacrolimus 52Prednisone 51Cyclosporine 50Antilymphocyte Serum 35dexamethasone acetate 32plerixafor 30Etoposide 30Methotrexate 29Radiotherapy 28dexamethasone 21-phosphate 27Doxorubicin 26

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × trametinib × Plasma cell × Clear all
NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

Novartis

Phase 2 Completed
206 enrolled 40 charts 2 FDA
CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

NCT01989598 2022-03-02

Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Relapsed or Refractory Multiple Myeloma

National Cancer Institute (NCI)

Phase 2 Completed
25 enrolled 11 charts
Plasma cell

Multiple Myeloma

NCT01476137 2017-11-13

A Study of the Safety and Activity of the MEK Inhibitor Given Together With the AKT Inhibitor to Patients With Multiple Myeloma or Solid Tumor Cancers

GlaxoSmithKline

Phase 1 Completed
335 enrolled
Plasma cell

Multiple Myeloma, Neoplasms

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