Announcements Trials
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Phase

Phase 1 2Phase 3 1Phase 1/2 1

Status

Completed 4

Sponsor Class

OTHER 2NIH 1NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 15Sarcoma 4

Conditions

Sarcoma 37Rhabdomyosarcoma 25Sarcoma, Ewing 18Dendritic Cell Sarcoma, Interdigitating 17Lymphoma 13Neuroectodermal Tumors, Primitive, Peripheral 10Lymphoma, Large B-Cell, Diffuse 10Neuroblastoma 8Malignant mesenchymal tumor 8HIV Infections 8Sarcoma, Kaposi 7Osteosarcoma 7Burkitt Lymphoma 7Acquired Immunodeficiency Syndrome 7Desmoplastic Small Round Cell Tumor 6Leukemia 5Wilms Tumor 4Neoplasms 4Lymphoma, Non-Hodgkin 4Central Nervous System Neoplasms 4Brain Neoplasms 4Astrocytoma 4Rhabdomyosarcoma, Embryonal 3Recurrence 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Liposarcoma 3Gliosarcoma 3Glioblastoma 3Fibrosarcoma 3Bone Neoplasms 3

Interventions

Temozolomide 45Radiotherapy 20Filgrastim 17Carmustine 15Carboplatin 15Irinotecan 13Bevacizumab 13Magnetic Resonance Spectroscopy 12Surgical Procedures, Operative 11Peripheral Blood Stem Cell Transplantation 9Erlotinib Hydrochloride 9sargramostim 8O(6)-benzylguanine 8Radiation 7Topotecan 6Thiotepa 6Radiotherapy, Intensity-Modulated 6Procarbazine 6Etoposide 6Drug Therapy 6Cyclophosphamide 6Chemotherapy, Adjuvant 6aldesleukin 5Vorinostat 5Sirolimus 5Imatinib Mesylate 5Granulocyte Colony-Stimulating Factor 5Busulfan 52-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 5temsirolimus 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Astrocytoma × Vincristine × Sarcoma × Clear all
NCT01837862 2024-07-05

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Northwell Health

Phase 1/2 Completed
36 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Gliosarcoma, Optic Nerve Glioma

NCT00005796 2015-03-25

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Indiana University

Phase 1 Completed
10 enrolled
CNSSarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma, Drug-Related Side Effects and Adverse Reactions

NCT00003141 2014-03-28

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

Children's Oncology Group

Phase 1 Completed
94 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Neuroblastoma, Sarcoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor

NCT00052455 2013-12-18

Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma

National Cancer Institute (NCI)

Phase 3 Completed
500 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

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