Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Phase 1/2 Terminated
53 enrolled 22 charts
Study of Pembrolizumab and M032 (NSC 733972)
Phase 1/2 Recruiting
28 enrolled
A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma
Phase 1/2 Completed
116 enrolled 31 charts
A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Phase 1/2 Completed
36 enrolled
Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
Phase 1/2 Terminated
7 enrolled 9 charts
AXL1717
Phase 1/2 Terminated
10 enrolled 8 charts
Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma
Phase 1/2 Completed
79 enrolled 17 charts
Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)
Phase 1/2 Terminated
21 enrolled 8 charts
Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma
Phase 1/2 Completed
36 enrolled 15 charts
Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been Removed By Surgery
Phase 1/2 Unknown
50 enrolled
Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Phase 1/2 Completed
122 enrolled 11 charts
Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas
Phase 1/2 Completed
66 enrolled 24 charts
Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma
Phase 1/2 Completed
35 enrolled 13 charts
SU5416 in Treating Patients With Recurrent Astrocytoma or Mixed Glioma That Has Not Responded to Radiation Therapy
Phase 1/2 Completed
Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma
Phase 1/2 Completed
105 enrolled
CCI-779 in Treating Patients With Malignant Glioma
Phase 1/2 Completed
49 enrolled
Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme
Phase 1/2 Completed
116 enrolled 17 charts
Phase I/II Cabazitaxel for Recurrent Malignant Glioma
Phase 1/2 Withdrawn
A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade Gliomas
Phase 1/2 Completed
57 enrolled 18 charts
Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma
Phase 1/2 Completed
136 enrolled 27 charts
Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma
Phase 1/2 Completed
257 enrolled 16 charts
A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB
Phase 1/2 Completed
76 enrolled 18 charts
FR901228 in Treating Patients With Recurrent High-Grade Gliomas
Phase 1/2 Completed
50 enrolled 6 charts
RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma
Phase 1/2 Terminated
13 enrolled 13 charts
Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma
Phase 1/2 Completed
62 enrolled 15 charts
Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma
Phase 1/2 Completed
69 enrolled 12 charts
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors
Phase 1/2 Completed
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers
Phase 1/2 Completed
Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm
Phase 1/2 Unknown
Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma
Phase 1/2 Completed
EMD 121974 in Treating Patients With Progressive or Recurrent Glioma
Phase 1/2 Completed
Immunotoxin Therapy in Treating Patients With Malignant Glioma
Phase 1/2 Completed
Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors
Phase 1/2 Completed
Irinotecan in Treating Patients With Recurrent Malignant Glioma
Phase 1/2 Completed
Procarbazine in Treating Patients With Recurrent Brain Tumor
Phase 1/2 Completed
COL-3 in Treating Patients With Progressive or Recurrent Brain Tumors
Phase 1/2 Completed
Efaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant Glioma
Phase 1/2 Completed
48 enrolled
Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors
Phase 1/2 Completed
30 enrolled
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors
Phase 1/2 Completed
10 enrolled
ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma
Phase 1/2 Completed
82 enrolled