Announcements Trials
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Phase

Phase 2 2Phase NA 1Phase 1 1

Status

Completed 3Withdrawn 1

Sponsor Class

NIH 2OTHER 1NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 20Sarcoma 4Lymphoid 4Other solid neoplasm 1Other hematologic neoplasm 1Dermatologic 1Breast 1

Conditions

Osteosarcoma 29Dendritic Cell Sarcoma, Interdigitating 25Lymphoma 20Burkitt Lymphoma 20Lymphoma, Large B-Cell, Diffuse 18Precursor Cell Lymphoblastic Leukemia-Lymphoma 16Lymphoma, Non-Hodgkin 16Leukemia 16Lymphoma, Large-Cell, Immunoblastic 15Lymphoma, Follicular 14Sarcoma 13Recurrence 13Multiple Myeloma 13Leukemia, Myeloid, Acute 13Leukemia, Lymphocytic, Chronic, B-Cell 13Lymphoma, Mantle-Cell 12Lymphoma, B-Cell, Marginal Zone 12Hodgkin Disease 12Neoplasms, Plasma Cell 11Myelodysplastic Syndromes 11Leukemia, Myeloid, Accelerated Phase 11Myeloproliferative Disorders 10Leukemia, Myelomonocytic, Chronic 10Congenital Abnormalities 10Leukemia, Myelomonocytic, Juvenile 9Leukemia, Myeloid, Chronic-Phase 9Blast Crisis 9Sezary Syndrome 8Primary Myelofibrosis 8Mycosis Fungoides 8

Interventions

Temozolomide 58Radiotherapy 50Carmustine 23Carboplatin 18Filgrastim 17Chemotherapy, Adjuvant 17Irinotecan 12Surgical Procedures, Operative 11Peripheral Blood Stem Cell Transplantation 11O(6)-benzylguanine 10Magnetic Resonance Spectroscopy 10Drug Therapy 10Etoposide 9sargramostim 8Thiotepa 8Thalidomide 8Cyclophosphamide 8Bevacizumab 8Procarbazine 7Gene Expression Profiling 7Erlotinib Hydrochloride 7Radiation 6Everolimus 6Cisplatin 6motexafin gadolinium 5aldesleukin 5Topotecan 5Imatinib Mesylate 5Celecoxib 5Busulfan 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Central Nervous System Neoplasms × Methotrexate × Sarcoma × Clear all
NCT00082797 2023-06-15

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Eastern Cooperative Oncology Group

Phase 2 Completed
36 enrolled
CNSSarcoma

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003273 2015-12-03

Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor

NYU Langone Health

Phase 2 Withdrawn
CNSOther solid neoplasmSarcoma

Neuroblastoma, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms

NCT00513981 2013-06-26

High-Dose Methotrexate in Treating Young Patients With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
36 enrolled
CNSSarcoma

Familial ependymoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms

NCT00463008 2013-06-24

Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma

National Cancer Institute (NCI)

Phase NA Completed
12 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

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