Clinical Trials

Phase 1 Active not recruiting

6 enrolled

LymphoidSarcoma

Chondrosarcoma, Lymphoma, Follicular

NCT04521686 2026-04-22

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

200 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Glioblastoma, Glioma, Melanoma, Prostatic Neoplasms, Thyroid Neoplasms, Central Nervous System Neoplasms, Cholangiocarcinoma

NCT05039801 2026-04-15

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Phase 1 Recruiting

54 enrolled

DermatologicGynecologicHead & NeckSarcoma

Squamous Cell Carcinoma of Head and Neck, Chondrosarcoma, Melanoma, Ovarian Neoplasms, Endometrial Neoplasms

NCT01267955 2026-04-13

Vismodegib in Treating Patients With Advanced Chondrosarcomas

45 enrolled 10 charts

Chondrosarcoma, Clear Cell, Chondrosarcoma, Chondrosarcoma, Mesenchymal

NCT00496522 2026-03-09

Proton Beam Therapy for Chondrosarcoma

CNSGastrointestinalSarcoma

Chondrosarcoma

NCT02073994 2026-02-17

Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation

Phase 1 Completed

174 enrolled

Chondrosarcoma, Glioma, Cholangiocarcinoma

NCT04055220 2026-02-17

REGOSTA

168 enrolled

Pathologic Complete Response, Bone Neoplasms, Chondrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Patient Compliance, Sarcoma, Ewing, Osteosarcoma, Histiocytoma, Malignant Fibrous

NCT06387485 2026-02-06

A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning

150 enrolled

Chondrosarcoma, Fibrosarcoma, Sarcoma, Ewing, Osteosarcoma, Histiocytoma, Benign Fibrous

NCT05861245 2026-01-23

Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base

20 enrolled

Phase NA Active not recruiting

Chondrosarcoma, Chordoma

NCT07360964 2026-01-22

CIRCLE

77 enrolled

Phase EARLY_PHASE1 Recruiting

Chondrosarcoma, Clear Cell, Chondrosarcoma

NCT06645808 2025-12-29

VARTUTRACE

32 enrolled

BreastCNSGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Stomach Neoplasms

NCT01449149 2025-12-05

Proton Radiation for Chordomas and Chondrosarcomas

Phase NA Completed

54 enrolled 11 charts

Phase 1 Active not recruiting

Chondrosarcoma, Chordoma

NCT03173976 2025-11-06

Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial

17 enrolled

Chondrosarcoma

NCT02389244 2025-09-16

REGOBONE

163 enrolled

Other solid neoplasmSarcoma

Chondroma, Chondrosarcoma, Osteosarcoma

NCT04040205 2025-07-20

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

Phase 2 Recruiting

44 enrolled

Chondrosarcoma, Retinoblastoma, Sarcoma, Osteosarcoma

NCT04553692 2025-03-28

Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants with Relapsed, Refractory, or Newly Diagnosed Cancers

Phase 1 Terminated

272 enrolled

GastrointestinalLymphoidOther hematologic neoplasmSarcoma

Chondrosarcoma, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Sarcoma, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute

NCT03474640 2024-11-22

Safety, Tolerability and Pharmacokinetics of an Anti-PD-1 Monoclonal Antibody in Subjects With Advanced Malignancies

Phase 1 Completed

184 enrolled 20 charts

GastrointestinalHead & NeckSarcoma

Nasopharyngeal Carcinoma, Chondrosarcoma, Esophageal Neoplasms, Carcinoma, Hepatocellular, Sarcoma, Stomach Neoplasms

NCT04673942 2024-10-26

BETA-PRIME

Phase 2 Recruiting

140 enrolled

Adenoviridae Infections, Chondrosarcoma, Neoplasms, Sarcoma

NCT06029218 2024-09-25

P1V2

106 enrolled

Chondrosarcoma, Chordoma, Sarcoma, Ewing, Osteosarcoma

NCT03277924 2024-08-13

ImmunoSarc

197 enrolled

Chondrosarcoma, Extraskeletal Myxoid, Bone Neoplasms, Chondrosarcoma, Hemangioendothelioma, Hemangiosarcoma, Leiomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Hemangioendothelioma, Epithelioid, Histiocytoma, Malignant Fibrous, Solitary Fibrous Tumors

NCT03670069 2024-05-08

Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas

Phase 1 Terminated

27 enrolled

Chondrosarcoma, Leiomyosarcoma, Sarcoma, Sarcoma, Synovial, Liposarcoma, Myxoid, Histiocytoma, Malignant Fibrous

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

78 enrolled 11 charts

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

NCT01336803 2023-12-27

Osteosarcoma

32 enrolled 11 charts

Bone Neoplasms, Chondrosarcoma, Osteomyelitis, Osteonecrosis, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT05448820 2023-09-21

YH001 Plus Envafolimab With or Without Doxorubicin in Patients With Advanced or Metastatic Sarcoma

Phase 1/2 Unknown

Diabetes Mellitus, Insulin-Dependent, 12, Chondrosarcoma, Sarcoma

NCT00003308 2023-06-22

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

CNSDermatologicGenitourinaryGynecologicSarcoma

Brain Neoplasms, Carcinoma, Renal Cell, Chondrosarcoma, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT05131386 2023-03-27

SYNERGIAS

Phase 2 Unknown

85 enrolled

Bone Neoplasms, Chondrosarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT01330966 2023-03-10

Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic Chondrosarcoma

47 enrolled 10 charts

Chondrosarcoma

NCT05193188 2023-02-16

A Study of Anlotinib Combined With or Without PD-1 Antibody on Unresectable High-grade Chondrosarcoma

Phase 2 Unknown

70 enrolled

Chondrosarcoma

NCT00543712 2022-12-13

A Study of PRO95780 in Patients With Advanced Chondrosarcoma (APM4171g)

Phase 2 Terminated

Chondrosarcoma, Sarcoma, Sarcoma, Synovial

NCT02273739 2021-02-23

Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation

CNSGastrointestinalSarcoma

21 enrolled 33 charts

Chondrosarcoma, Glioma, Immunoblastic Lymphadenopathy, Cholangiocarcinoma

NCT04260113 2021-01-05

AIAC

Phase NA Completed

40 enrolled

Chondrosarcoma, Drug-Related Side Effects and Adverse Reactions

NCT04690725 2020-12-31

TQBSP

Phase 1/2 Unknown

29 enrolled

Chondrosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT04098887 2020-09-16

Lattice Stereotactic Body Radiation Therapy (Lattice SBRT) for Localized Unresectable or Metastatic Conventional Type Chondrosarcoma

Phase NA Withdrawn

Chondrosarcoma

NCT02496741 2020-01-09

MACIST

CNSGastrointestinalSarcoma

Chondrosarcoma, Glioma, Cholangiocarcinoma

NCT01883518 2019-11-20

ADCVCTAST

Phase 1/2 Unknown

48 enrolled

Chondrosarcoma, Fibrosarcoma, Leiomyosarcoma, Liposarcoma, Myosarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Neoplasms, Connective and Soft Tissue, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Histiocytoma, Malignant Fibrous

NCT00949325 2019-03-11

Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma

24 enrolled 14 charts

Phase EARLY_PHASE1 Terminated

Chondrosarcoma, Leiomyosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT00499733 2019-01-18

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

19 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Osteosarcoma, Tongue Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Intraocular Lymphoma

NCT00464620 2018-11-23

Trial of Dasatinib in Advanced Sarcomas

366 enrolled 16 charts

GastrointestinalSarcoma

Chondrosarcoma, Chordoma, Hemangiopericytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Giant Cell Tumor of Bone, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Gastrointestinal Stromal Tumors, Solitary Fibrous Tumors

NCT01560260 2018-09-21

Linsitinib in Treating Patients With Gastrointestinal Stromal Tumors

CNSEndocrineGastrointestinalSarcoma

20 enrolled 15 charts

Chondrosarcoma, Paraganglioma, Gastrointestinal Stromal Tumors, Carney Complex

NCT01154452 2018-08-15

Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

78 enrolled 11 charts

GastrointestinalSarcoma

Malignant mesenchymal tumor, Chondrosarcoma, Extraskeletal Myxoid, Chondrosarcoma, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Sarcoma, Synovial, Dermatofibrosarcoma, Sarcoma, Alveolar Soft Part, Neuroectodermal Tumors, Primitive, Peripheral, Neurofibrosarcoma, Hemangioendothelioma, Epithelioid, Gastrointestinal Stromal Tumors, Histiocytoma, Malignant Fibrous, Desmoplastic Small Round Cell Tumor

NCT01553539 2018-07-05

Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery

20 enrolled 10 charts

Bone Neoplasms, Chondrosarcoma, Sarcoma, Osteosarcoma

NCT03491371 2018-04-10

Apatinib for Advanced Sarcoma: Results From Multiple Institutions' Off-label Use

Phase NA Completed

56 enrolled

Chondrosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT00401388 2018-03-07

A Trial of Perifosine in Patients With Chemo-Insensitive Sarcomas

72 enrolled

Chondrosarcoma, Sarcoma, Alveolar Soft Part

NCT02982486 2017-11-01

A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma

Phase 2 Unknown

60 enrolled

GastrointestinalSarcoma

Bone Neoplasms, Chondrosarcoma, Sarcoma, Osteosarcoma, Gastrointestinal Stromal Tumors, Desmoplastic Small Round Cell Tumor

NCT02008019 2017-08-07

CHONRAD

Phase 2 Suspended

57 enrolled

Chondrosarcoma

NCT00592748 2017-06-16

Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine

381 enrolled

Chondrosarcoma, Chordoma

NCT00003657 2017-01-20

High-dose ICE With Amifostine

CNSGenitourinaryGynecologicHead & NeckSarcomaThoracic

24 enrolled

AIDS-related Kaposi sarcoma, Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Chondrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Ovarian Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT00550654 2017-01-13

Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the Brain

Phase 2 Terminated

1 enrolled 7 charts

DermatologicGenitourinaryGynecologicSarcoma

Carcinoma, Renal Cell, Chondrosarcoma, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Osteosarcoma

NCT00450736 2016-12-15

Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery

Phase 1 Completed

3 enrolled