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Phase

Phase 1 1

Status

Withdrawn 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Sarcoma 16Central Nervous System Neoplasms 10Gliosarcoma 9Glioblastoma 9Osteosarcoma 8Astrocytoma 6Sarcoma, Ewing 5Neoplasms 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma 3Lung Neoplasms 3Breast Neoplasms 3Brain Neoplasms 3Waldenstrom Macroglobulinemia 2Stomach Neoplasms 2Recurrence 2Pancreatic Neoplasms 2Ovarian Neoplasms 2Oligodendroglioma 2Neoplasm Metastasis 2Multiple Myeloma 2Melanoma 2Lymphoma, Extranodal NK-T-Cell 2Liver Neoplasms 2Leukemia, Myelomonocytic, Juvenile 2Leukemia 2Glioma 2Esophageal Neoplasms 2Dendritic Cell Sarcoma, Interdigitating 2Colorectal Neoplasms 2

Interventions

Filgrastim 7Temozolomide 6Carboplatin 6Peripheral Blood Stem Cell Transplantation 5Cyclophosphamide 4Magnetic Resonance Spectroscopy 3Etoposide 3Cisplatin 3etoposide phosphate 2Vincristine 2Thiotepa 2Radiotherapy 2Paclitaxel 2Granulocyte Colony-Stimulating Factor 2Gadolinium DTPA 2Donepezil 2Cyproheptadine 2Bortezomib 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 2temsirolimus 1sargramostim 1ixabepilone 1ispinesib 1gallium Ga 68 dotatate 1gadobutrol 1gadobenic acid 1exatecan 1entinostat 1carboxyamido-triazole 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Choroid Plexus Neoplasms × Drug Therapy × Sarcoma × Clear all
NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Children's Oncology Group

Phase 1 Withdrawn
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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