Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Lymphoid 2CNS 2Other hematologic neoplasm 1

Conditions

Gliosarcoma 7Glioblastoma 6Sarcoma 5Brain Neoplasms 5Astrocytoma 5Oligodendroglioma 4Neuroblastoma 3Glioma 3Wilms Tumor 2Recurrence 2Neoplasm Metastasis 2Medulloblastoma 2Lymphoma, Large B-Cell, Diffuse 2Dendritic Cell Sarcoma, Interdigitating 2Burkitt Lymphoma 2Sarcoma, Ewing 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Optic Nerve Glioma 1Neoplasms, Germ Cell and Embryonal 1Neoplasms 1Meningioma 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, Extranodal NK-T-Cell 1Lymphoma 1Leukemia, Myelomonocytic, Juvenile 1Leiomyosarcoma 1Hepatoblastoma 1Familial ependymoma 1

Interventions

Cyclophosphamide 76fludarabine phosphate 42Filgrastim 38Peripheral Blood Stem Cell Transplantation 35Radiotherapy 33Cyclosporine 32Busulfan 32Mycophenolic Acid 30Etoposide 30Antilymphocyte Serum 28Whole-Body Irradiation 26Methotrexate 25Rituximab 22Melphalan 21Methylprednisolone 20Vincristine 17Tacrolimus 17Cytarabine 17Cord Blood Stem Cell Transplantation 17Doxorubicin 16Prednisone 15Thiotepa 10Granulocyte Colony-Stimulating Factor 9Carboplatin 8Leucovorin 7fludarabine 6aldesleukin 6Ifosfamide 6sargramostim 5Sirolimus 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Dendritic Cell Sarcoma, Interdigitating × Vorinostat × Sarcoma × Clear all
NCT00217412 2014-06-17

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

National Cancer Institute (NCI)

Phase 1 Completed
60 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Medulloblastoma, Neuroblastoma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

NCT00994500 2013-07-02

Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma

National Cancer Institute (NCI)

Phase 1 Completed
20 enrolled
CNSLymphoidSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Meningioma, Oligodendroglioma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

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