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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other solid neoplasm 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Sarcoma 43Melanoma 19Neoplasms 12Squamous Cell Carcinoma of Head and Neck 11Neoplasm Metastasis 11Carcinoma, Non-Small-Cell Lung 9Breast Neoplasms 9Glioblastoma 8Colorectal Neoplasms 8Triple Negative Breast Neoplasms 7Pancreatic Neoplasms 7Ovarian Neoplasms 7Gliosarcoma 7Lung Neoplasms 6Histiocytoma, Malignant Fibrous 6Carcinoma, Renal Cell 6Osteosarcoma 5Liposarcoma 5Head and Neck Neoplasms 5Carcinoma, Hepatocellular 5Uterine Cervical Neoplasms 4Sarcoma, Synovial 4Sarcoma, Kaposi 4Neurofibrosarcoma 4Lymphoma 4Hemangiosarcoma 4Carcinoma, Merkel Cell 4Urinary Bladder Neoplasms 3Stomach Neoplasms 3Recurrence 3

Interventions

Cyclophosphamide 9Doxorubicin 8Vincristine 6Etoposide 6Ifosfamide 5Filgrastim 5Radiotherapy 4fludarabine phosphate 3Topotecan 3Thiotepa 3Peripheral Blood Stem Cell Transplantation 3Melphalan 3Cisplatin 3Carboplatin 3seclidemstat 2Temozolomide 2Tacrolimus 2Neoadjuvant Therapy 2Irinotecan 2Injections 2Hyperthermic Intraperitoneal Chemotherapy 2Granulocyte Colony-Stimulating Factor 2Epirubicin 2Dactinomycin 2Cytoreduction Surgical Procedures 2Cyclosporine 2Chemotherapy, Adjuvant 2Brachytherapy 2thymoglobulin 1tazemetostat 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Desmoplastic Small Round Cell Tumor × pembrolizumab × Sarcoma × Clear all
NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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