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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 3Sarcoma 1Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Gliosarcoma 15Glioblastoma 15Central Nervous System Neoplasms 10Brain Neoplasms 9Astrocytoma 8Glioma 6Oligodendroglioma 4Sarcoma 2Ependymoma 2Wilms Tumor 1Testicular Neoplasms 1Teratoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Medulloblastoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma 1Liver Neoplasms 1Leukemia, Lymphocytic, Chronic, B-Cell 1

Interventions

Filgrastim 10Temozolomide 5Peripheral Blood Stem Cell Transplantation 5sargramostim 4Carboplatin 4Thiotepa 3Cyclophosphamide 3Busulfan 3Topotecan 2Radiotherapy 2Oxaliplatin 2Melphalan 2Irinotecan 2Ifosfamide 2Granulocyte Colony-Stimulating Factor 2Etoposide 2Cyproheptadine 2Cisplatin 2trioctyl phosphine oxide 1palbociclib 1olaparib 1ixabepilone 1ispinesib 1gallium Ga 68 dotatate 1exatecan 1etoposide phosphate 1becatecarin 1alvocidib 1aldesleukin 1Vorinostat 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Familial ependymoma × O(6)-benzylguanine × Sarcoma × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

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