Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 3Sarcoma 2Other hematologic neoplasm 1Lymphoid 1Genitourinary 1

Conditions

Sarcoma 15Sarcoma, Ewing 10Neuroblastoma 7Rhabdomyosarcoma 6Osteosarcoma 6Gliosarcoma 6Glioblastoma 6Brain Neoplasms 6Astrocytoma 6Neuroectodermal Tumors, Primitive, Peripheral 5Medulloblastoma 5Central Nervous System Neoplasms 5Glioma 4Wilms Tumor 3Sarcoma, Clear Cell 3Rhabdoid Tumor 3Recurrence 3Desmoplastic Small Round Cell Tumor 3Dendritic Cell Sarcoma, Interdigitating 3Burkitt Lymphoma 3Testicular Neoplasms 2Retinoblastoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Ovarian Neoplasms 2Optic Nerve Glioma 2Oligodendroglioma 2Myoepithelioma 2Meningeal Carcinomatosis 2Malignant mesenchymal tumor 2Lymphoma 2

Interventions

Filgrastim 10Temozolomide 5Peripheral Blood Stem Cell Transplantation 5sargramostim 4Carboplatin 4Thiotepa 3Cyclophosphamide 3Busulfan 3Topotecan 2Radiotherapy 2Oxaliplatin 2Melphalan 2Irinotecan 2Ifosfamide 2Granulocyte Colony-Stimulating Factor 2Etoposide 2Cyproheptadine 2Cisplatin 2trioctyl phosphine oxide 1palbociclib 1olaparib 1ixabepilone 1ispinesib 1gallium Ga 68 dotatate 1exatecan 1etoposide phosphate 1becatecarin 1alvocidib 1aldesleukin 1Vorinostat 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Familial ependymoma × Topotecan × Sarcoma × Clear all
NCT00638898 2025-03-20

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

City of Hope Medical Center

Phase 1 Completed
25 enrolled
CNSGenitourinarySarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00112619 2011-06-30

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Pediatric Brain Tumor Consortium

Phase 1 Terminated
19 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Neoplasms, Unknown Primary, Oligodendroglioma, Recurrence, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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