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Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT07134842 2026-04-09

WinGlio-ipi

Phase 1 Recruiting

16 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Phase 2 Recruiting

36 enrolled

CNSSarcoma

Astrocytoma, Glioblastoma, Gliosarcoma

NCT06934889 2026-03-30

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

Phase 1 Recruiting

60 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT03896568 2026-03-05

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Phase 1 Recruiting

36 enrolled

CNSSarcoma

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

NCT05756985 2026-02-04

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

Recruiting

120 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT04991870 2026-01-23

Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM

Phase 1 Recruiting

25 enrolled

Sarcoma

Gliosarcoma

NCT05084430 2026-01-22

Study of Pembrolizumab and M032 (NSC 733972)

Phase 1/2 Recruiting

28 enrolled

CNSSarcoma

Astrocytoma, Glioblastoma, Recurrence, Gliosarcoma

NCT05465954 2026-01-12

Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma

Phase 2 Recruiting

54 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT05039281 2025-12-19

Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma

Phase 1/2 Recruiting

6 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Phase 1 Recruiting

102 enrolled

CNSSarcoma

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

NCT04555577 2025-10-29