Announcements Trials
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Phase

Phase 2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Myeloid 1Lymphoid 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Sarcoma 9Rhabdoid Tumor 6Sarcoma, Synovial 5Lymphoma, Non-Hodgkin 4Wilms Tumor 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neuroblastoma 2Mesothelioma 2Medulloblastoma 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, Follicular 2Histiocytosis, Langerhans-Cell 2Hepatoblastoma 2Glioma 2Ependymoma 2Central Nervous System Neoplasms 2Xanthogranuloma, Juvenile 1Tertiary Lymphoid Structures 1Pancreatic Neoplasms 1Neurofibrosarcoma 1Nerve Sheath Neoplasms 1Neoplasms 1Mesothelioma, Malignant 1Inhibition, Psychological 1Hodgkin Disease 1Histiocytic Sarcoma 1Hematologic Neoplasms 1

Interventions

Cyclophosphamide 42fludarabine phosphate 33Peripheral Blood Stem Cell Transplantation 32Mycophenolic Acid 26Whole-Body Irradiation 23Cyclosporine 23Busulfan 23Radiotherapy 19Filgrastim 19Antilymphocyte Serum 19Tacrolimus 16Melphalan 16Methotrexate 12Methylprednisolone 10Cord Blood Stem Cell Transplantation 10Etoposide 8Thiotepa 6sargramostim 5fludarabine 5Therapeutics 5aldesleukin 4Sirolimus 4Cytarabine 4Polymerase Chain Reaction 3Paclitaxel 3Granulocyte Colony-Stimulating Factor 3Carmustine 3Amplified Fragment Length Polymorphism Analysis 3Alemtuzumab 3thymoglobulin 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Hodgkin Disease × tazemetostat × Sarcoma × Clear all
NCT03213665 2026-04-13

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

Phase 2 Completed
20 enrolled 12 charts
CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Hodgkin Disease, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

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