Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Lymphoid 19Other hematologic neoplasm 10Myeloid 6Plasma cell 5Other neoplasm 3Sarcoma 2Dermatologic 2Genitourinary 1

Conditions

Sarcoma 434Osteosarcoma 131Sarcoma, Ewing 89Melanoma 81Rhabdomyosarcoma 78Neoplasms 70Gastrointestinal Stromal Tumors 63Neuroblastoma 62Bone Neoplasms 62Colorectal Neoplasms 60Breast Neoplasms 60Ovarian Neoplasms 58Glioblastoma 55Neoplasm Metastasis 52Liposarcoma 49Dendritic Cell Sarcoma, Interdigitating 44Carcinoma, Non-Small-Cell Lung 44Gliosarcoma 42Stomach Neoplasms 40Pancreatic Neoplasms 40Leiomyosarcoma 40Lymphoma 37Glioma 35Carcinoma, Renal Cell 35Sarcoma, Synovial 34Rhabdoid Tumor 34Neurofibrosarcoma 34Uterine Cervical Neoplasms 33Sarcoma, Kaposi 33Lymphoma, Non-Hodgkin 33

Interventions

pembrolizumab 1Cyclophosphamide 1ARQ531 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Immune System Diseases × Sarcoma × 1 year × Clear all
NCT03349450 2026-05-06

SPiReL

Sunnybrook Health Sciences Centre

Phase 2 Completed
25 enrolled 18 charts
LymphoidSarcoma

Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Recurrence, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Dendritic Cell Sarcoma, Interdigitating

NCT03162536 2025-09-08

ARQ 531-101

ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)

Phase 1/2 Active not recruiting
190 enrolled
LymphoidOther hematologic neoplasmPlasma cellSarcoma

Blood Protein Disorders, Cardiovascular Diseases, Hemorrhagic Disorders, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Lymphatic Diseases, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Recurrence, Vascular Diseases, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Hematologic Neoplasms, Hemostatic Disorders, Lymphoma, Mantle-Cell, Neoplasms, Plasma Cell, Dendritic Cell Sarcoma, Interdigitating

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