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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Gynecologic 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Gliosarcoma 15Glioblastoma 15Central Nervous System Neoplasms 10Brain Neoplasms 9Astrocytoma 8Glioma 6Oligodendroglioma 4Sarcoma 2Ependymoma 2Wilms Tumor 1Testicular Neoplasms 1Teratoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Medulloblastoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma 1Liver Neoplasms 1Leukemia, Lymphocytic, Chronic, B-Cell 1

Interventions

Filgrastim 4Carboplatin 4Thiotepa 3pembrolizumab 2ixabepilone 2Temozolomide 2Riluzole 2Radiotherapy 2Peripheral Blood Stem Cell Transplantation 2Oncolytic Virotherapy 2Melphalan 2Ipilimumab 2Ifosfamide 2Granulocyte Colony-Stimulating Factor 2Etoposide 2Drug Therapy 2Cyclophosphamide 2Busulfan 2trastuzumab deruxtecan 1spartalizumab 1sodium thiosulfate 1sargramostim 1pazopanib 1fludarabine 1etoposide phosphate 1Topotecan 1Thrombopoietin 1Tamoxifen 1Stem Cell Transplantation 1Restraint, Physical 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Liver Neoplasms × O(6)-benzylguanine × Sarcoma × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

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